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RNA interference : application to drug discovery and challenges to pharmaceutical development / edited by Paul H. Johnson. - Hoboken : John Wiley & Sons, ©2011. - xvi, 450 pages : illustrations

Includes bibliographical references and index.

Frontmatter -- Color Plates -- Biology of RNA Interference. RNA Interference: What is it? / James A Birchler -- Nucleic Acids as Regulatory Molecules / Faqing Huang, C J Yu, Yanlin Guo -- Use of SiRNA Oligonucleotides to Study Gene Function / Kristin A Wiederholt, Adam N Harris -- Genome Scanning by RNA Interference / Roderick L Beijersbergen, Oliver C Steinbach -- Development of SiRNA for Therapeutic Applications. Discovery of New SiRNA Delivery Agents / Paul H Johnson, Diane Frank, Kunyuan Cui, Roger Adami, Harry Wang, Michael Houston, Steven C Quay -- SiRNA Delivery Vehicles / Aliasger K Salem, Mark A Behlke -- Interferon, Cytokine Induction, and other Potential Toxicities / Adam Judge, Marjorie Robbins, Ian Maclachlan -- Application of RNA Interference to Viral Diseases / Ralph A Tripp, Stephen Mark Tompkins -- Index.


Electronic reproduction.
Hoboken, N.J. :
Wiley InterScience,
2011.
Mode of access: World Wide Web.
System requirements: Web browser.
Title from title screen (viewed on Jan. 4, 2011).
Access may be restricted to users at subscribing institutions.

ISBN: 9780470923733 0470923733

Standard No.: 10.1002/9780470923733 doi

Source: 10.1002/9780470923733 Wiley InterScience http://www3.interscience.wiley.com

Subjects--Topical Terms:
Drug development.
RNA editing.
Drug development.
RNA editing.

Index Terms--Genre/Form:
Electronic books.

LC Class. No.: RM301.25 / .R63 2011

Dewey Class. No.: 615/.19