Epigenetic Alterations in Oncogenesis (Record no. 43460)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 03311nam a22004937a 4500 |
| 001 - CONTROL NUMBER | |
| control field | sulb-eb0021368 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | BD-SySUS |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20160413122141.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 120905s2013 xxu| s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9781441999672 |
| -- | 978-1-4419-9967-2 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1007/978-1-4419-9967-2 |
| Source of number or code | doi |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | RC261-271 |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MJCL |
| Source | bicssc |
| Subject category code | MED062000 |
| Source | bisacsh |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 614.5999 |
| Edition number | 23 |
| 245 10 - TITLE STATEMENT | |
| Title | Epigenetic Alterations in Oncogenesis |
| Medium | [electronic resource] / |
| Statement of responsibility, etc. | edited by Adam R. Karpf. |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Place of production, publication, distribution, manufacture | New York, NY : |
| Name of producer, publisher, distributor, manufacturer | Springer New York : |
| -- | Imprint: Springer, |
| Date of production, publication, distribution, manufacture, or copyright notice | 2013. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | XVI, 348 p. |
| Other physical details | online resource. |
| 336 ## - CONTENT TYPE | |
| Content type term | text |
| Content type code | txt |
| Source | rdacontent |
| 337 ## - MEDIA TYPE | |
| Media type term | computer |
| Media type code | c |
| Source | rdamedia |
| 338 ## - CARRIER TYPE | |
| Carrier type term | online resource |
| Carrier type code | cr |
| Source | rdacarrier |
| 347 ## - DIGITAL FILE CHARACTERISTICS | |
| File type | text file |
| Encoding format | |
| Source | rda |
| 490 1# - SERIES STATEMENT | |
| Series statement | Advances in Experimental Medicine and Biology, |
| International Standard Serial Number | 0065-2598 ; |
| Volume/sequential designation | 754 |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Preface -- Section I: Epigenetic Marks and Mechanisms -- DNA methyltransferases (DNMTs), DNA damage repair, and cancer -- DNA hypomethylation and hemimethylation in cancer -- Ten Eleven Translocation (TET) Enzymes and 5-hydroxymethylation in Mammalian Development and Cancer -- Altered histone modifications in cancer -- Nucleosome occupancy and gene regulation during tumorigenesis -- Section II: The Impact of Epigenetic Alterations on Cancer Biology -- Epigenetic regulation of miRNAs in cancer -- DNA hypomethylation and activation of germline-specific genes in cancer -- APC and DNA demethylation in cell fate specification and intestinal cancer -- Epigenetic changes during cell transformation -- Epigenetic reprogramming of mesenchymal stem cells -- Section III: Clinical Implications and Analysis Methods -- Environmental toxicants, epigenetics, and cancer -- Blood derived DNA methylation markers of cancer risk -- Epigenetic therapies in MDS and AML -- Epigenetic targeting therapies to overcome chemotherapy resistance -- Methods for cancer epigenome analysis -- Index. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | The purpose of this book is to provide an up to date review of the nature and consequences of epigenetic changes in cancer. Epigenetics literally means “above” genetics, and consists of heritable gene expression or other phenotypic states not accounted for by DNA base sequence. Epigenetic changes are now known to make a large contribution to various aspects of tumorigenesis. These changes include alterations in global and promoter specific DNA methylation, activating and repressive histone modifications, and changes in higher order chromatin structures. Each of these topics will be covered in this book. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Medicine. |
| Topical term or geographic name as entry element | Cancer research. |
| Topical term or geographic name as entry element | Human genetics. |
| Topical term or geographic name as entry element | Oncology. |
| Topical term or geographic name as entry element | Biomedicine. |
| Topical term or geographic name as entry element | Cancer Research. |
| Topical term or geographic name as entry element | Human Genetics. |
| Topical term or geographic name as entry element | Oncology. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Karpf, Adam R. |
| Relator term | editor. |
| 710 2# - ADDED ENTRY--CORPORATE NAME | |
| Corporate name or jurisdiction name as entry element | SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY | |
| Title | Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Relationship information | Printed edition: |
| International Standard Book Number | 9781441999665 |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE | |
| Uniform title | Advances in Experimental Medicine and Biology, |
| International Standard Serial Number | 0065-2598 ; |
| Volume number/sequential designation | 754 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://dx.doi.org/10.1007/978-1-4419-9967-2">http://dx.doi.org/10.1007/978-1-4419-9967-2</a> |
| 912 ## - | |
| -- | ZDB-2-SBL |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | |
| Koha item type | |
No items available.