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DNA Helicases and DNA Motor Proteins (Record no. 44254)

MARC details
000 -LEADER
fixed length control field 03760nam a22005297a 4500
001 - CONTROL NUMBER
control field sulb-eb0022162
003 - CONTROL NUMBER IDENTIFIER
control field BD-SySUS
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20160413122228.0
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field cr nn 008mamaa
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 121117s2013 xxu| s |||| 0|eng d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9781461450375
-- 978-1-4614-5037-5
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.1007/978-1-4614-5037-5
Source of number or code doi
050 #4 - LIBRARY OF CONGRESS CALL NUMBER
Classification number RB155-155.8
Classification number QH431
072 #7 - SUBJECT CATEGORY CODE
Subject category code MFN
Source bicssc
Subject category code MED107000
Source bisacsh
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 611.01816
Edition number 23
Classification number 599.935
Edition number 23
245 10 - TITLE STATEMENT
Title DNA Helicases and DNA Motor Proteins
Medium [electronic resource] /
Statement of responsibility, etc. edited by Maria Spies.
264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE
Place of production, publication, distribution, manufacture New York, NY :
Name of producer, publisher, distributor, manufacturer Springer New York :
-- Imprint: Springer,
Date of production, publication, distribution, manufacture, or copyright notice 2013.
300 ## - PHYSICAL DESCRIPTION
Extent XII, 304 p.
Other physical details online resource.
336 ## - CONTENT TYPE
Content type term text
Content type code txt
Source rdacontent
337 ## - MEDIA TYPE
Media type term computer
Media type code c
Source rdamedia
338 ## - CARRIER TYPE
Carrier type term online resource
Carrier type code cr
Source rdacarrier
347 ## - DIGITAL FILE CHARACTERISTICS
File type text file
Encoding format PDF
Source rda
490 1# - SERIES STATEMENT
Series statement Advances in Experimental Medicine and Biology,
International Standard Serial Number 0065-2598 ;
Volume/sequential designation 973
505 0# - FORMATTED CONTENTS NOTE
Formatted contents note Preface -- Overview: What are DNA helicases? -- Structure and mechanisms of SF1 DNA helicases -- Structure and mechanisms of SF2 DNA helicases -- Structure and mechanisms of hexameric helicases -- Helicases at the replication fork -- DNA helicases associated with genetic instability, cancer and aging -- The Helicase-primase complex as a target for effective herpesvirus antivirals -- RecQ helicases - conserved guardians of genetic integrity -- Roles of DNA helicases in the mediation and rRegulation of homologous recombination -- DNA helicases in NER, BER and MMR -- Roles for helicases as ATP-dependent molecular switches -- The FtsK family of DNA pumps -- ATP dependent chromatin remodelers -- Index.
520 ## - SUMMARY, ETC.
Summary, etc. In recent years, a number of groundbreaking structural and mechanistic studies deepened our understanding of helicase mechanisms and established new approaches for their analyses. Many fundamental mechanistic questions ranging from the mechanism of force generation, mechanochemical coupling to distinct mechanisms by which the same enzyme translocates on DNA removing obstacles, unwinds DNA and/or remodels nucleoprotein complexes, however, remain to be answered. It is even less understood how the helicase motors are incorporated into a wide range of genome maintenance and repair machines. The field has reached a stage when the studies of molecular mechanisms and basic biology of helicases can and shall be integrated with the studies of development, cancer and longevity. The objective of this book is to provide the first systematic overview of structure, function and regulation of DNA helicases and related molecular motors. By integrating the knowledge obtained through the diverse technical approaches ranging from single-molecule biophysics to cellular and molecular biological studies the editors aim to provide a unified view on how helicases function in the cell, are regulated in response to different cellular stresses and are integrated into large macromolecular assemblies to form a complex and adaptive living system.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Medicine.
Topical term or geographic name as entry element Human genetics.
Topical term or geographic name as entry element Biochemistry.
Topical term or geographic name as entry element Cell biology.
Topical term or geographic name as entry element Biomedicine.
Topical term or geographic name as entry element Human Genetics.
Topical term or geographic name as entry element Biochemistry, general.
Topical term or geographic name as entry element Cell Biology.
Topical term or geographic name as entry element Biomedicine general.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Spies, Maria.
Relator term editor.
710 2# - ADDED ENTRY--CORPORATE NAME
Corporate name or jurisdiction name as entry element SpringerLink (Online service)
773 0# - HOST ITEM ENTRY
Title Springer eBooks
776 08 - ADDITIONAL PHYSICAL FORM ENTRY
Relationship information Printed edition:
International Standard Book Number 9781461450368
830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE
Uniform title Advances in Experimental Medicine and Biology,
International Standard Serial Number 0065-2598 ;
Volume number/sequential designation 973
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="http://dx.doi.org/10.1007/978-1-4614-5037-5">http://dx.doi.org/10.1007/978-1-4614-5037-5</a>
912 ## -
-- ZDB-2-SBL
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme
Koha item type

No items available.