Ten Years of Progress in GW/P Body Research (Record no. 44276)
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| fixed length control field | 03412nam a22005297a 4500 |
| 001 - CONTROL NUMBER | |
| control field | sulb-eb0022184 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | BD-SySUS |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20160413122230.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 121207s2013 xxu| s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9781461451075 |
| -- | 978-1-4614-5107-5 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1007/978-1-4614-5107-5 |
| Source of number or code | doi |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | RB155-155.8 |
| Classification number | QH431 |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MFN |
| Source | bicssc |
| Subject category code | MED107000 |
| Source | bisacsh |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 611.01816 |
| Edition number | 23 |
| Classification number | 599.935 |
| Edition number | 23 |
| 245 10 - TITLE STATEMENT | |
| Title | Ten Years of Progress in GW/P Body Research |
| Medium | [electronic resource] / |
| Statement of responsibility, etc. | edited by Edward K. L. Chan, Marvin J. Fritzler. |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Place of production, publication, distribution, manufacture | New York, NY : |
| Name of producer, publisher, distributor, manufacturer | Springer New York : |
| -- | Imprint: Springer, |
| Date of production, publication, distribution, manufacture, or copyright notice | 2013. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | XII, 276 p. |
| Other physical details | online resource. |
| 336 ## - CONTENT TYPE | |
| Content type term | text |
| Content type code | txt |
| Source | rdacontent |
| 337 ## - MEDIA TYPE | |
| Media type term | computer |
| Media type code | c |
| Source | rdamedia |
| 338 ## - CARRIER TYPE | |
| Carrier type term | online resource |
| Carrier type code | cr |
| Source | rdacarrier |
| 347 ## - DIGITAL FILE CHARACTERISTICS | |
| File type | text file |
| Encoding format | |
| Source | rda |
| 490 1# - SERIES STATEMENT | |
| Series statement | Advances in Experimental Medicine and Biology, |
| International Standard Serial Number | 0065-2598 ; |
| Volume/sequential designation | 768 |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Preface -- The GW body Story as an Example of Autoantibodies with Significant Impacts to Molecular Cell Biology -- The Discovery of GW Bodies -- The Discovery and Analysis of P Bodies -- Autoantibodies to Argonaute 2 (Su antigen) -- GW/P Bodies and Autoimmune Disease -- Function of GW182 and GW Bodies in siRNA and miRNA Pathways -- Post-Transcriptional Stimulation of Gene Expression by MicroRNAs -- Gawky (Gw) is the Drosophila Melanogaster GW182 Homologue -- The Role of GW182 Proteins in miRNA-mediated Gene Silencing -- Quantifying Argonaute Proteins in and out of GW/P-bodies: Implications in microRNA Activities -- Deadenylation and P-bodies -- Relationship of GW/P-bodies with Stress Granules -- Relationship of other Cytoplasmic Ribonucleoprotein (RNP) Bodies to GW/P Bodies -- A SNP in the Trinucleotide Repeat Region of the TNRC6A Gene Maps to a Major TNGW1 Autoepitope in Patients with Autoantibodies to GW182 -- Reflections on Ten Years of History of, and Future Prospects for, GW182 and GW/P Body Research -- Index. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | GW bodies are novel cytoplasmic foci that were discovered and named by Dr. Chan’s group in 2002. These bodies are now known to be active cytoplasmic foci involved with the new gene regulation process mediated by microRNA that leads to translational repression and mRNA degradation. The detailed biological functions of these cytoplasmic structures are still being uncovered and the idea for this book is to provide the history of the discovery and the major work from different laboratories that has led to the characterization and elucidation of the structure and function of these new multiple subcellular structures. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Medicine. |
| Topical term or geographic name as entry element | Human genetics. |
| Topical term or geographic name as entry element | Biochemistry. |
| Topical term or geographic name as entry element | Cell biology. |
| Topical term or geographic name as entry element | Biomedicine. |
| Topical term or geographic name as entry element | Human Genetics. |
| Topical term or geographic name as entry element | Cell Biology. |
| Topical term or geographic name as entry element | Biochemistry, general. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Chan, Edward K. L. |
| Relator term | editor. |
| Personal name | Fritzler, Marvin J. |
| Relator term | editor. |
| 710 2# - ADDED ENTRY--CORPORATE NAME | |
| Corporate name or jurisdiction name as entry element | SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY | |
| Title | Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Relationship information | Printed edition: |
| International Standard Book Number | 9781461451068 |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE | |
| Uniform title | Advances in Experimental Medicine and Biology, |
| International Standard Serial Number | 0065-2598 ; |
| Volume number/sequential designation | 768 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://dx.doi.org/10.1007/978-1-4614-5107-5">http://dx.doi.org/10.1007/978-1-4614-5107-5</a> |
| 912 ## - | |
| -- | ZDB-2-SBL |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | |
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No items available.