Kisspeptin Signaling in Reproductive Biology (Record no. 44569)
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| fixed length control field | 04047nam a22005177a 4500 |
| 001 - CONTROL NUMBER | |
| control field | sulb-eb0022477 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | BD-SySUS |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20160413122259.0 |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr nn 008mamaa |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 130403s2013 xxu| s |||| 0|eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9781461461999 |
| -- | 978-1-4614-6199-9 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1007/978-1-4614-6199-9 |
| Source of number or code | doi |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | R-RZ |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MBGR |
| Source | bicssc |
| Subject category code | MED000000 |
| Source | bisacsh |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 610 |
| Edition number | 23 |
| 245 10 - TITLE STATEMENT | |
| Title | Kisspeptin Signaling in Reproductive Biology |
| Medium | [electronic resource] / |
| Statement of responsibility, etc. | edited by Alexander S. Kauffman, Jeremy T. Smith. |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Place of production, publication, distribution, manufacture | New York, NY : |
| Name of producer, publisher, distributor, manufacturer | Springer New York : |
| -- | Imprint: Springer, |
| Date of production, publication, distribution, manufacture, or copyright notice | 2013. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | XII, 514 p. |
| Other physical details | online resource. |
| 336 ## - CONTENT TYPE | |
| Content type term | text |
| Content type code | txt |
| Source | rdacontent |
| 337 ## - MEDIA TYPE | |
| Media type term | computer |
| Media type code | c |
| Source | rdamedia |
| 338 ## - CARRIER TYPE | |
| Carrier type term | online resource |
| Carrier type code | cr |
| Source | rdacarrier |
| 347 ## - DIGITAL FILE CHARACTERISTICS | |
| File type | text file |
| Encoding format | |
| Source | rda |
| 490 1# - SERIES STATEMENT | |
| Series statement | Advances in Experimental Medicine and Biology, |
| International Standard Serial Number | 0065-2598 ; |
| Volume/sequential designation | 784 |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Part One: Kisspeptin Signaling in vivo and in vitro -- Kisspeptin: Past, Present and Prologue -- Structure, Synthesis, and Phylogeny of Kisspeptin and its Receptor -- Neuroanatomy of the Kisspeptin Signaling System in Mammals: Comparative and Developmental Aspects -- The Effects of Kisspeptin on Gonadotropin Release in Non-Human Mammals -- Effects of Kisspeptin on Hormone Secretion in Humans -- Kisspeptin Excitation of GnRH Neurons -- Molecular Biology of the Kisspeptin Receptor: Signaling, Function, and Mutations -- Kisspeptin Antagonists -- Kisspeptin and Clinical Disorders -- Beyond the GnRH Axis: Kisspeptin Regulation of the Oxytocin System in Pregnancy and Lactation -- Part Two: Development and Regulation of Kisspeptin Neurons -- The Development of Kisspeptin Circuits in the Mammalian Brain -- Kisspeptin and Puberty in Mammals -- Sex Steroid Regulation of Kisspeptin Circuits -- Kisspeptin and GnRH Pulse Generation -- Interactions between Kisspeptins and Neurokinin B -- Electrophysiology of Kisspeptin Neurons -- Metabolic Regulation of Kisspeptin -- Circadian Regulation of Kisspeptin in Female Reproductive Functioning -- Kisspeptin and Seasonality of Reproduction -- Stress Regulation of Kisspeptin in the Modulation of Reproductive Function -- Effects of Environmental Endocrine Disruptors and Phytoestrogens on the Kisspeptin System -- Model Systems for Studying Kisspeptin Signaling: Mice and Cells -- Index. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Kisspeptin has been shown to be both necessary and sufficient for activation of the reproductive axis, during puberty and later in adulthood. This makes kisspeptin a fundamental component of the reproductive axis. Kisspeptin has been deemed the single most potent stimulator of GnRH neurons yet known. The importance of kisspeptin has been documented in humans as well as non-human animal models, ranging from monkeys, sheep, and rodents to numerous fish species, thus signifying a highly conserved nature of its reproductive function. Importantly, kisspeptin neurons seem to mediate many of the regulatory effects of other signals, whether they are metabolic, circadian, hormonal, or stress. This places kisspeptin neurons in a unique position to be key nodal points and conduits for conveying numerous endogenous and exogenous signals to the reproductive axis. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Medicine. |
| Topical term or geographic name as entry element | Neurosciences. |
| Topical term or geographic name as entry element | Endocrinology. |
| Topical term or geographic name as entry element | Reproductive medicine. |
| Topical term or geographic name as entry element | Biomedicine. |
| Topical term or geographic name as entry element | Biomedicine general. |
| Topical term or geographic name as entry element | Endocrinology. |
| Topical term or geographic name as entry element | Reproductive Medicine. |
| Topical term or geographic name as entry element | Neurosciences. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Kauffman, Alexander S. |
| Relator term | editor. |
| Personal name | Smith, Jeremy T. |
| Relator term | editor. |
| 710 2# - ADDED ENTRY--CORPORATE NAME | |
| Corporate name or jurisdiction name as entry element | SpringerLink (Online service) |
| 773 0# - HOST ITEM ENTRY | |
| Title | Springer eBooks |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Relationship information | Printed edition: |
| International Standard Book Number | 9781461461982 |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE | |
| Uniform title | Advances in Experimental Medicine and Biology, |
| International Standard Serial Number | 0065-2598 ; |
| Volume number/sequential designation | 784 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://dx.doi.org/10.1007/978-1-4614-6199-9">http://dx.doi.org/10.1007/978-1-4614-6199-9</a> |
| 912 ## - | |
| -- | ZDB-2-SBL |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
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No items available.