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Stress-Induced Mutagenesis (Record no. 44592)

MARC details
000 -LEADER
fixed length control field 03274nam a22004817a 4500
001 - CONTROL NUMBER
control field sulb-eb0022500
003 - CONTROL NUMBER IDENTIFIER
control field BD-SySUS
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20160413122301.0
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field cr nn 008mamaa
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 130321s2013 xxu| s |||| 0|eng d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9781461462804
-- 978-1-4614-6280-4
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.1007/978-1-4614-6280-4
Source of number or code doi
050 #4 - LIBRARY OF CONGRESS CALL NUMBER
Classification number RB155-155.8
Classification number QH431
072 #7 - SUBJECT CATEGORY CODE
Subject category code MFN
Source bicssc
Subject category code MED107000
Source bisacsh
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 611.01816
Edition number 23
Classification number 599.935
Edition number 23
245 10 - TITLE STATEMENT
Title Stress-Induced Mutagenesis
Medium [electronic resource] /
Statement of responsibility, etc. edited by David Mittelman.
264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE
Place of production, publication, distribution, manufacture New York, NY :
Name of producer, publisher, distributor, manufacturer Springer New York :
-- Imprint: Springer,
Date of production, publication, distribution, manufacture, or copyright notice 2013.
300 ## - PHYSICAL DESCRIPTION
Extent XV, 275 p.
Other physical details online resource.
336 ## - CONTENT TYPE
Content type term text
Content type code txt
Source rdacontent
337 ## - MEDIA TYPE
Media type term computer
Media type code c
Source rdamedia
338 ## - CARRIER TYPE
Carrier type term online resource
Carrier type code cr
Source rdacarrier
347 ## - DIGITAL FILE CHARACTERISTICS
File type text file
Encoding format PDF
Source rda
505 0# - FORMATTED CONTENTS NOTE
Formatted contents note Preface -- Stress-induced mutagenesis in bacteria -- Mutagenesis Associated with Repair of DNA Double-Strand Breaks Under Stress -- Transcription-mediated mutagenic processes -- Transposon mutagenesis in disease, drug discovery and bacterial evolution -- Hsp90 as a capacitor of both genetic and epigenetic changes in the genome during cancer progression and evolution -- Inheritance of stress-induced epigenetic changes mediated by the ATF-2 family of transcription factors -- Microsatellite Repeats: Canaries in the Coalmine -- Genetic instability Induced by hypoxic stress -- Radiation-induced delayed genome Instability and hypermutation in mammalian cells -- Radiation-induced bystander effects and stress-induced mutagenesis -- Stress induced mutagenesis, genetic diversification, and cell survival via anastasis, the reversal of late stage apoptosis -- The transgenerational effects of parental exposure to mutagens in mammals -- Revisiting mutagenesis in the age of high-throughput sequencing -- Index.
520 ## - SUMMARY, ETC.
Summary, etc. The discoveries of stress-induced mutation and epigenetic inheritance have challenged the claim of independence between the evolutionary forces of mutation and selection. In “Stress-Induced Mutagenesis”, leading experts provide the key evidence for and the molecular details of stress-induced genetic and epigenetic mutation, integrating cross-disciplinary observations from a number of species and biological systems, including human. The observations have vast implications for evolutionary biology but also for human medicine. A comprehensive understanding of stress-induced mutagenesis and the processes underlying evolvability, will enable gains in the treatment and management of cancer, as well as other human disorders that result from damaged or unstable genomes.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Medicine.
Topical term or geographic name as entry element Human genetics.
Topical term or geographic name as entry element Biochemistry.
Topical term or geographic name as entry element Biomedicine.
Topical term or geographic name as entry element Human Genetics.
Topical term or geographic name as entry element Biochemistry, general.
Topical term or geographic name as entry element Biomedicine general.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Mittelman, David.
Relator term editor.
710 2# - ADDED ENTRY--CORPORATE NAME
Corporate name or jurisdiction name as entry element SpringerLink (Online service)
773 0# - HOST ITEM ENTRY
Title Springer eBooks
776 08 - ADDITIONAL PHYSICAL FORM ENTRY
Relationship information Printed edition:
International Standard Book Number 9781461462798
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="http://dx.doi.org/10.1007/978-1-4614-6280-4">http://dx.doi.org/10.1007/978-1-4614-6280-4</a>
912 ## -
-- ZDB-2-SBL
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme
Koha item type

No items available.