TY  - BOOK
AU  - Melchor,Max García
ED  - SpringerLink (Online service)
TI  - A Theoretical Study of Pd-Catalyzed C-C Cross-Coupling Reactions
T2  - Springer Theses, Recognizing Outstanding Ph.D. Research,
SN  - 9783319014906
AV  - QD450-801 
U1  - 541.2 23
PY  - 2013///
CY  - Cham
PB  - Springer International Publishing, Imprint: Springer
KW  - Chemistry
KW  - Organic chemistry
KW  - Chemistry, Physical and theoretical
KW  - Catalysis
KW  - Theoretical and Computational Chemistry
KW  - Organic Chemistry
N1  - General introduction -- Computational methods -- Objectives -- The Negishi reaction mechanism -- The Cu-free Sonogashira reaction mechanism -- An asymmetric Suzuki-Miyaura reaction mechanism -- General conclusions
N2  - Find out how theoretical calculations are used to determine, elucidate and propose mechanisms for Pd-catalyzed C-C cross-coupling reactions in Max Garcia Melchor's outstanding thesis. Garcia Melchor investigates one of the most significant and useful types of reactions in modern organic synthesis; the Pd-cross coupling reaction. Due to its versatility, broad scope and selectivity under mild conditions, this type of reaction can now be applied in fields as diverse as the agrochemical and pharmaceutical industry. Garcia Melchor studies the reaction intermediates and transition states involved in the Negishi, the copper-free Sonogashira and the asymmetric version of Suzuki-Miyaura coupling. He also characterizes and provides a detailed picture of the associated reaction mechanisms. The author has won numerous prizes for this work which has led to over eight publications in internationally renowned journals
UR  - http://dx.doi.org/10.1007/978-3-319-01490-6
ER  -