TY - BOOK AU - Johnson,Paul H. ED - Wiley InterScience (Online service) TI - RNA interference: application to drug discovery and challenges to pharmaceutical development SN - 9780470923733 AV - RM301.25 .R63 2011 U1 - 615/.19 22 PY - 2011/// CY - Hoboken PB - John Wiley & Sons KW - Drug development KW - RNA editing KW - fast KW - Electronic books N1 - Includes bibliographical references and index; Frontmatter -- Color Plates -- Biology of RNA Interference. RNA Interference: What is it? / James A Birchler -- Nucleic Acids as Regulatory Molecules / Faqing Huang, C J Yu, Yanlin Guo -- Use of SiRNA Oligonucleotides to Study Gene Function / Kristin A Wiederholt, Adam N Harris -- Genome Scanning by RNA Interference / Roderick L Beijersbergen, Oliver C Steinbach -- Development of SiRNA for Therapeutic Applications. Discovery of New SiRNA Delivery Agents / Paul H Johnson, Diane Frank, Kunyuan Cui, Roger Adami, Harry Wang, Michael Houston, Steven C Quay -- SiRNA Delivery Vehicles / Aliasger K Salem, Mark A Behlke -- Interferon, Cytokine Induction, and other Potential Toxicities / Adam Judge, Marjorie Robbins, Ian Maclachlan -- Application of RNA Interference to Viral Diseases / Ralph A Tripp, Stephen Mark Tompkins -- Index; Electronic reproduction; Hoboken, N.J.; Wiley InterScience; 2011; Mode of access: World Wide Web; System requirements: Web browser; Title from title screen (viewed on Jan. 4, 2011); Access may be restricted to users at subscribing institutions UR - http://onlinelibrary.wiley.com/book/10.1002/9780470923733 ER -