TY - BOOK AU - Manmohan Singh, AU - Srivasta,Indresh K. TI - Development of Vaccines: From Discovery to Clinical Testing SN - 9781118023648 AV - QR189 .D48 2011 U1 - 615/.372 22 PY - 2011/// CY - Hoboken, N.J. PB - John Wiley & Sons KW - Vaccines KW - Drug development KW - Drug stability KW - MEDICAL KW - Pharmacology KW - bisacsh KW - fast KW - pharmacology KW - Drug Discovery KW - methods KW - Drug Stability KW - Electronic books N1 - Includes bibliographical references and index; Microbial vaccines design : the reverse vaccinology approach; Roberto Rosini, Michele A. Barocchi, Rino Rappuoli --; Design and development of recombinant vaccines with viral properties; Gerd Lipowsky, Martin F. Bachmann --; Tools for vaccine design : prediction and validation of highly immunogenic and conserved class II epitopes, and development of epitope-driven vaccines; Anne S. De Groot [and others] --; Virus like-particle vaccines advantages and challenges; Ted M. Ross [and others] --; Design platforms of nanocapsules for human therapeutics or vaccines; Masaaki Kawano [and others] --; Designing immunogens for vaccine development in reference to HIV; Aemro Kassa [and others]; Expression and purification of recombinant proteins for vaccine applications; Carlo Zambonelli, Deeann Martinez-Guzmann, and Indresh K. Srivastava --; DNA vaccines for infectious diesase; Samuel Stepenson, Manmohan Singh, Indresh K. Srivastava --; Developing stable cell lines for the production of vaccine antigens; Xiaotian Zhong [and others] --; Spectroscopy of vaccines; C. Russell Middaugh, Sangeeta B. Joshi --; Biophysical characterization of protein antigens within vaccine formulations; Padima Malyala, Derek O'Hagan, Manmohan Singh --; Structural characteristics predict the stability of HIV; Zohar Biron [and others] --; Selection of optimal adjuvants and product factors that affect vaccine immunogenicity; Wei Wang, Manmohan Singh --; Lyophilization and stabilization of vaccines; James Chesko [and others] --; Effect of buffers and stabilizers on vaccine stability and efficacy; Shireesh P. Apte, Sydney Ugwu --; Selection of final product containers; Luis Baez, Adrian Distler --; From the lab to the clinic : filing a phase I IND for an investigational vaccine; Kenneth G. Surowitz UR - http://onlinelibrary.wiley.com/book/10.1002/9781118023648 ER -