TY - BOOK AU - Brown,Sarah R. AU - Gregory,Walter M. AU - Twelves,Chris AU - Brown,Julia TI - A practical guide to designing phase II trials in oncology T2 - Statistics in practice SN - 9781118763636 (ePub) AV - RC271.C5 U1 - 616.99/4061 23 PY - 2014/// CY - Chichester, West Sussex PB - John Wiley & Sons Inc. KW - Clinical Trials, Phase II as Topic KW - Antineoplastic Agents KW - therapeutic use KW - Drug Evaluation KW - methods KW - Neoplasms KW - drug therapy KW - Clinical trials KW - Antineoplastic agents KW - Therapeutic use KW - Tumors KW - Treatment KW - HEALTH & FITNESS KW - Diseases KW - General KW - bisacsh KW - MEDICAL KW - Clinical Medicine KW - Evidence-Based Medicine KW - Internal Medicine KW - fast KW - Electronic books N1 - Includes bibliographical references and index N2 - "Choosing Your Phase II Trial Design provides an overview to clinical trial researchers of the steps involved in designing a phase II trial and provides a way to identify a range of optimal designs. Providing a practical guide containing the information needed to make crucial decisions regarding phase II trial designs, it sets forth specific points for consideration between the statistician and clinician when designing a phase II trial, including issues such as how the treatment works, choice of outcome measure and randomisation. A detailed library of trial designs is featured along with examples and case studies accompanied by illustrations using a flow diagram, highlighting the choices made for each key point throughout the process. For those new to trial design, the book provides an introduction to the concepts behind informed decision making in phase II trials, offering a unique and practical learning tool. For those familiar with phase II trial design, the reader will benefit from exposure to new, less familiar trial designs, providing alternative options to those which the reader may not have previously used"--Provided by publisher UR - http://onlinelibrary.wiley.com/book/10.1002/9781118763612 ER -