TY  - BOOK
AU  - Kirchmair,Johannes
TI  - Drug metabolism prediction
T2  - Methods and Principles in Medicinal Chemistry
SN  - 9783527673261
AV  - RM301.55 .D784 2014eb
U1  - 615.7 23
PY  - 2014///
CY  - Weinheim, Germany
PB  - Wiley-VCH
KW  - Drugs
KW  - Metabolism
KW  - Enzymes
KW  - Effect of drugs on
KW  - MEDICAL
KW  - Pharmacology
KW  - bisacsh
KW  - fast
KW  - Electronic books
N1  - Includes bibliographical references at the end of each chapters and index; Part 1. Introduction -- Part 2. Software, web servers and data resources to study metabolism -- Part 3. Computational approaches to study cytochrome P450 enzymes -- Part 4. Computational approaches to study sites and products of metabolism -- Part 5. Computational approaches to study enzymes inhibition and induction -- Part 6. Experimental approaches to study metabolism
N2  - The first professional reference on this highly relevant topic, for drug developers, pharmacologists and toxicologists. The authors provide more than a systematic overview of computational tools and knowledge bases for drug metabolism research and their underlying principles. They aim to convey their expert knowledge distilled from many years of experience in the field. In addition to the fundamentals, computational approaches and their applications, this volume provides expert accounts of the latest experimental methods for investigating drug metabolism in four dedicated chapters. The authors
UR  - http://onlinelibrary.wiley.com/book/10.1002/9783527673261
ER  -