TY  - BOOK
AU  - Schedl,Tim
ED  - SpringerLink (Online service)
TI  - Germ Cell Development in C. elegans
T2  - Advances in Experimental Medicine and Biology,
SN  - 9781461440154
AV  - RB155-155.8 
U1  - 611.01816 23
PY  - 2013///
CY  - New York, NY
PB  - Springer New York, Imprint: Springer
KW  - Medicine
KW  - Human genetics
KW  - Cell biology
KW  - Developmental biology
KW  - Biomedicine
KW  - Human Genetics
KW  - Cell Biology
KW  - Developmental Biology
N1  - Introduction to germ cell development in C. elegans -- Germ cell specification -- Sex determination in the C. elegans germline -- Stem cell proliferation versus meiotic fate decision in C. elegans -- Physiological control of germline development -- Meiotic development in C. elegans -- Spermatogenesis -- Translational control in the C. elegans germ line -- Germ cell apoptosis and DNA damage responses -- Control of Oocyte Growth and Meiotic Maturation in C. elegans -- Fertilization -- The oocyte-to-embryo transition -- Epigenetic Control of Germline Development -- Using Caenorhabditis to explore the evolution of the germ line -- Index
N2  - Germ cells in sexually reproducing metazoa, through the germline lineage, are the route by which genetic material and cytoplasmic constituents are passed from one generation to the next in the continuum of life.  Chapters in this book review germ cell development in the model organism Caenorhabditis elegans, discussing the biology, the genetics and the molecular mechanisms for various processes, as well as drawing comparisons with other organisms.  Processes discussed include specification of germ cell fate, meiosis, gametogenesis, environmental/ physiological controls, epigenetics and translational control, fertilization and the oocyte-to-embryo transition.  This book thus provides a comprehensive picture of the germline lineage and the continuum of life for the worm
UR  - http://dx.doi.org/10.1007/978-1-4614-4015-4
ER  -