TY  - BOOK
AU  - Praticὸ,Domenico
AU  - Mecocci,Patrizia
ED  - SpringerLink (Online service)
TI  - Studies on Alzheimer's Disease
T2  - Oxidative Stress in Applied Basic Research and Clinical Practice,
SN  - 9781627035989
AV  - QH573-671 
U1  - 571.9453 23
PY  - 2013///
CY  - Totowa, NJ
PB  - Humana Press, Imprint: Humana Press
KW  - Life sciences
KW  - Geriatrics
KW  - Cell biology
KW  - Oxidative stress
KW  - Life Sciences
KW  - Oxidative Stress
KW  - Cell Biology
KW  - Geriatrics/Gerontology
N1  - Section 1: Hypotheses -- Oxidative stress: impact in neuroscience research -- Oxidative stress and Alzheimer’s disease -- Inflammation and Oxidation: a link in Alzheimer’ disease pathogenesis -- GAPDH:β-amyloid mediated iron accumulation in Alzheimer’s disease -- Aβ in mitochondria: one piece in the Alzheimer’s disease puzzle -- The role of the plasma membrane redox system in the pathognesis of Alzheimer’s disease -- Section 2: Mechanisms -- Metal dysfunction in Alzheimer’s disease -- Brain Oxidative Stress in the Pathogenesis and Progression of Alzheimer’s Disease -- Cholesterol metabolism and oxidative stress in Alzheimer’s disease -- Brain hypometabolism, oxidative stress, maternal transmission and risk of late-onset Alzheimer’s disease -- Stress and HPA axis dysfunction in Alzheimer’s disease -- Section 3: Clinics -- Diabetes mellitus and its impact on sporadic Alzheimer’s disease -- Peripheral biomarkers of oxidative tress in Alzheimer’s disease -- Nutrition lifestyle and oxidative stress: prevention in Alzheimer’s disease -- Are antioxidants food and nutrients useful in preventing cognitive decline?.- Antioxidant clinical trials in Mild Cognitive Impairment and Alzheimer’s disease
N2  - Dr. Domenico Praticò received his M.D. from the University of Rome “La Sapienza,” School of Medicine. He is currently a Professor of Pharmacology, Microbiology and Immunology and member of the Center for Translational Medicine at Temple University. His main research interest is oxidative biology with a particular focus on bioactive lipids, their metabolic pathways, and their role as biological mediators of cellular and molecular events in the pathogenesis of human diseases, including neurodegenerative and cardiovascular diseases.   Dr. Patrizia Mecocci received her M.D. from the University of Perugia, School of Medicine. She is currently a Full Professor of Gerontology and Geriatrics and Director of the Geriatric Clinic at the University of Perugia. Her research is devoted mainly to clinical geriatrics, with a specific interest on brain aging and dementia and on age-related biological modifications, with a particular focus on the role of oxidants and antioxidants in neurodegenerative and cardiovascular diseases. 
UR  - http://dx.doi.org/10.1007/978-1-62703-598-9
ER  -