Oxidative stress and antioxidant protection : the science of free radical biology & disease / edited by Donald Armstrong, Robert D. Stratton.

Includes bibliographical references and index.

Print version record and CIP data provided by publisher.

Machine generated contents note: 1. Introduction to Free Radicals, Inflammation, and Recycling, -- 2. Diagnostic Imaging and Differential Diagnosis, / Donald Armstrong -- 3. Free Radicals: Their Role in Brain Function and Dysfunction, / Robert D. Stratton -- 4. Mediators of Neuroinflammation, / Natan Gadoth -- 5. Oxidative and Nitrative Stress in Schizophrenia, / Bin Liu / Ping Zhang / Rajiv Tikamdas -- 6. The Effects of Hypoxia, Hyperoxia, and Oxygen Fluctuations on Oxidative Signaling in the Preterm Infant and on Retinopathy of Prematurity, / Anna Dietrich-Muszalska -- 7. Oxidative Damage in the Retina, / M. Elizabeth Hartnett -- 8. The Role of Oxidative Stress in Hearing Loss, / Robert D. Stratton -- 9. Disorders of Children, / Colleen G. Le Prell / Josef M. Miller -- 10. Oxidative Stress in Oral Cavity: Interplay between Reactive Oxygen Species and Antioxidants in Health, Inflammation, and Cancer, / Masato Yashiro / Hirokazu Tsukahara -- 11. Oxidative Stress and the Skin, / Bogdan Calenic / Maria Greabu / Maurizio Battino -- 12. Oxidative Stress in Osteoarticular Diseases, / Christina L. Mitchell -- 13. Gene Therapy to Reduce Joint Inflammation in Horses, / Maria José Alcaraz / Sergio Portal-Núñez / Juan A. Ardura / Pedro Esbrit -- 14. Muscle and Oxidative Stress, / Patrick Colahan / Steve Ghivizzani / Rachael Watson -- 15. Role of Oxidants and Antioxidants in Male Reproduction, / Mitra Hariri / Reza Ghiasvand -- 16. Role of Oxidants and Antioxidants in Female Reproduction, / Aaron Panicker / Eva Tvrdá / Hanna Tadros / Ashok Agarwal -- 17. Reactive Oxygen Species, Oxidative Stress, and Cardiovascular Diseases, / Ashok Agarwal / Eva Tvrdá / Hanna Tadros -- 18. Oxidative Stress and Antioxidant Imbalance: Respiratory Disorders, / Fatemeh Sharifpanah / Heinrich Sauer -- 19. Oxidative Stress and Type 1 Diabetes, / Surinder K. Jindal -- 20. Metabolic Syndrome, Inflammation, and Reactive Oxygen Species in Children and Adults, / Jing Chen / Chao Liu / Clayton E. Mathews -- 21. Oxidative Stress in Chronic Pancreatitis, / William E. Winter / Janet H. Silverstein -- 22. Wound Healing and Hyperbaric Oxygen Therapy Physiology: Oxidative Damage and Antioxidant Imbalance, / Bechan Sharma / Shweta Singh -- 23. Radiobiology and Radiotherapy, / James R. Wilcox / D. Scott Covington -- 24. Chemotherapy-Mediated Pain and Peripheral Neuropathy: Impact of Oxidative Stress and Inflammation, / Judith Lightsey / Justin Wray -- 25. Grape Polyphenol-rich Products with Antioxidant and Anti-inflammatory Properties, / Hassan A.N. El-Fawal / Robert Rembisz / Shaker A. Mousa / Ryyan Alobaidi -- 26. Isotonic Oligomeric Proanthocyanidins, / Elena Falqué / Herminia Dominguez / Eduarda Fernandes / Marisa Freitas / Renan C. Chisté -- 27. Superoxide Dismutase Mimics and Other Redox-active Therapeutics, / Donald Armstrong / Hanbo Hu -- 28. Herbal Medicine: Past, Present, and Future with Emphasis on the Use of Some Common Species, / Artak Tovmasyan / Ines Batinic-Haberle -- 29. Ayurvedic Perspective on Oxidative Stress Management, / Aneela Afzal / Mohammad Afzal -- 30. Clinical Trials and Antioxidant Outcomes, / Priyanka M. Jadhav -- 31. Statistical Approaches to Make Decisions in Clinical Experiments, / Carlos Palacio / Arshag D. Mooradian.

Oxidative Stress and Antioxidant Protection: The Science of Free Radical Biology and Disease provides an overview of the basic principles of free radical formation. The text delves into free radical formation in molecular biology and its effect on subcellular damage, as well as the role of antioxidant reserves as a protective mechanism.

Oxidative Stress and Antioxidant Protection begins with a historical perspective of pioneers in oxidative stress with an introductory section that explains the basic principles related to oxidative stress in biochemistry and molecular biology, demonstrating both pathways and biomarkers. This section also covers diagnostic imaging and differential diagnostics. The following section covers psychological, physiologic, pharmacologic and pathologic correlates. This section addresses inheritance, gender, nutrition, obesity, family history, behavior modification, natural herbal-botanical products, and supplementation in the treatment of disease. Clinical trials are also summarized for major medical disorders and efficacy of treatment, with particular focus on inflammation, immune response, recycling, disease progression, outcomes, and interventions. Each of the chapters describes what biomarker(s) and physiological functions may be relevant to a concept of specific disease and potential alternative therapy. The chapters cover medical terminology, developmental change, effects of aging, senescence, lifespan, and wound healing, and also illustrate cross-over exposure to other fields. The final chapter covers how and when to interpret appropriate data used in entry-level biostatistics and epidemiology.

Authored and edited by leaders in the field, Oxidative Stress and Antioxidant Protection will be an invaluable resource for students and researchers studying cell biology, molecular biology, and biochemistry as well as for professionals in various health science fields.

Takes a translational approach to oxidative stress research.

Provides a broad coverage of disease.

A concluding section covers how and when to interpret appropriate data used in entry-level biostatistics and epidemiology, a "toolbox" application, as well as principles of biotechnology, our most promising advance for drug delivery.

Summarizes clinical trials for major medical disorders and efficacy of treatment.

Stimulates more directions for student applications in their professional careers --Book Jacket.