000 | 02189nam a22003497a 4500 | ||
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001 | sulb-eb0015734 | ||
003 | BD-SySUS | ||
005 | 20160405134443.0 | ||
008 | 110218s2013||||enk o ||1 0|eng|d | ||
020 | _a9781139026451 (ebook) | ||
020 | _z9781107008809 (hardback) | ||
020 | _z9781107401358 (paperback) | ||
040 |
_aUkCbUP _beng _erda _cUkCbUP |
||
050 | 0 | 0 |
_aR853.C55 _bG46 2013 |
082 | 0 | 0 |
_a610.72/4 _223 |
100 | 1 |
_aSimon, Richard M., _eauthor. |
|
245 | 1 | 0 |
_aGenomic Clinical Trials and Predictive Medicine / _cRichard M. Simon. |
246 | 3 | _aGenomic Clinical Trials & Predictive Medicine | |
264 | 1 |
_aCambridge : _bCambridge University Press, _c2013. |
|
300 |
_a1 online resource (153 pages) : _bdigital, PDF file(s). |
||
336 |
_atext _btxt _2rdacontent |
||
337 |
_acomputer _bc _2rdamedia |
||
338 |
_aonline resource _bcr _2rdacarrier |
||
490 | 0 | _aPractical Guides to Biostatistics and Epidemiology | |
500 | _aTitle from publisher's bibliographic system (viewed on 04 Apr 2016). | ||
520 | _aGenomics is majorly impacting therapeutics development in medicine. This book contains up-to-date information on the use of genomics in the design and analysis of therapeutic clinical trials with a focus on novel approaches that provide a reliable basis for identifying which patients are most likely to benefit from each treatment. It is oriented to both clinical investigators and statisticians. For clinical investigators, it includes background information on clinical trial design and statistical analysis. For statisticians and others who want to go deeper, it covers state-of-the-art adaptive designs and the development and validation of probabilistic classifiers. The author describes the development and validation of prognostic and predictive biomarkers and their integration into clinical trials that establish their clinical utility for informing treatment decisions for future patients. | ||
650 | 0 | _aResearch Design | |
776 | 0 | 8 |
_iPrint version: _z9781107008809 |
830 | 0 | _aPractical Guides to Biostatistics and Epidemiology. | |
856 | 4 | 0 | _uhttp://dx.doi.org/10.1017/CBO9781139026451 |
942 |
_2Dewey Decimal Classification _ceBooks |
||
999 |
_c37578 _d37578 |