000 | 03504nam a22005537a 4500 | ||
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001 | sulb-eb0021904 | ||
003 | BD-SySUS | ||
005 | 20160413122209.0 | ||
007 | cr nn 008mamaa | ||
008 | 120905s2013 xxu| s |||| 0|eng d | ||
020 |
_a9781461439646 _9978-1-4614-3964-6 |
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024 | 7 |
_a10.1007/978-1-4614-3964-6 _2doi |
|
050 | 4 | _aQH506 | |
072 | 7 |
_aMBGR _2bicssc |
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072 | 7 |
_aPSD _2bicssc |
|
072 | 7 |
_aSCI049000 _2bisacsh |
|
072 | 7 |
_aMED067000 _2bisacsh |
|
082 | 0 | 4 |
_a611.01816 _223 |
100 | 1 |
_aTeng, Quincy. _eauthor. |
|
245 | 1 | 0 |
_aStructural Biology _h[electronic resource] : _bPractical NMR Applications / _cby Quincy Teng. |
250 | _a2nd ed. 2013. | ||
264 | 1 |
_aBoston, MA : _bSpringer US : _bImprint: Springer, _c2013. |
|
300 |
_aXIV, 434 p. _bonline resource. |
||
336 |
_atext _btxt _2rdacontent |
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337 |
_acomputer _bc _2rdamedia |
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338 |
_aonline resource _bcr _2rdacarrier |
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347 |
_atext file _bPDF _2rda |
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505 | 0 | _aBasic Principles of NMR -- Instrumentation -- NMR Sample Preparation -- Practical Aspects -- Multi-Dimensional Heteronuclear NMR Experiments -- Studies Of Small Biological Molecules -- Protein Structure Determination From NMR Data -- Protein Dynamics -- NMR-based Metabolomics. | |
520 | _aOver the years since NMR was first applied to solve problems in structural biology, both NMR instrument hardware and methodology have been dramatically developed. This book offers a much-needed update to the 2005 first edition, and will be of critical importance to those who routinely use NMR to study various biological systems as well as a textbook. Thus, the book is organized with experimentalists in mind, whether they are instructors or students. For those who have minimal background in NMR structural biology, this book will provide fresh perspective and insight; those who are already well-versed in NMR research will find cutting edge updates and new information and methods that are useful to their research. Because understanding fundamental principles and concepts of NMR spectroscopy is essential for the application of NMR methods to research projects, the book begins with an introduction to basic NMR principles. Next, NMR instrumentation is discussed starting with hardware components. Topics include magnetic field homogeneity and stability, signal generation and detection, probe circuits, cryogenic probe, analog-to-digital conversion, and test equipment. A typical specification for a NMR spectrometer is also included in the chapter. There is also a chapter covering NMR sample preparation, a process that is often the bottleneck for the success of the NMR projects. Several routine strategies for preparing samples, especially for macromolecules as well as complexes are dealt with in detail. | ||
650 | 0 | _aMedicine. | |
650 | 0 | _aMolecular biology. | |
650 | 0 | _aBiotechnology. | |
650 | 0 | _aBiochemistry. | |
650 | 0 | _aBiophysics. | |
650 | 0 | _aBiological physics. | |
650 | 1 | 4 | _aBiomedicine. |
650 | 2 | 4 | _aMolecular Medicine. |
650 | 2 | 4 | _aBiomedicine general. |
650 | 2 | 4 | _aBiophysics and Biological Physics. |
650 | 2 | 4 | _aBiochemistry, general. |
650 | 2 | 4 | _aBiotechnology. |
710 | 2 | _aSpringerLink (Online service) | |
773 | 0 | _tSpringer eBooks | |
776 | 0 | 8 |
_iPrinted edition: _z9781461439639 |
856 | 4 | 0 | _uhttp://dx.doi.org/10.1007/978-1-4614-3964-6 |
912 | _aZDB-2-SBL | ||
942 |
_2Dewey Decimal Classification _ceBooks |
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999 |
_c43996 _d43996 |