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007			cr nn 008mamaa
008			120821s2013 xxu| s |||| 0|eng d
020			_a9781461440277 _9978-1-4614-4027-7
024	7		_a10.1007/978-1-4614-4027-7 _2doi
050		4	_aR-RZ
072		7	_aMBGR _2bicssc
072		7	_aMED000000 _2bisacsh
082	0	4	_a610 _223
245	1	0	_aMechanisms and Emerging Therapies in Tremor Disorders _h[electronic resource] / _cedited by Giuliana Grimaldi, Mario Manto.
264		1	_aNew York, NY : _bSpringer New York : _bImprint: Springer, _c2013.
300			_aXVI, 492 p. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
490	1		_aContemporary Clinical Neuroscience
505	0		_aPart 1: Fundamental aspects -- Definition of tremor -- Membrane mechanisms of tremor -- Rodent models of tremor -- Advances in genetics of human tremor -- Musculo-skeletal models of tremor -- Part 2: The various forms of tremor in clinical practice: presentation and mechanism -- Physiological tremor -- Rest tremor -- Postural tremors -- Isometric tremor -- Essential Tremor and Other Forms of Kinetic Tremor -- Dystonic tremor -- Orthostatic tremor -- Vocal tremor -- Update in Familial Cortical Myoclonic tremor with Epilepsy (FCMTE) -- Post-traumatic tremor and Other Post-Traumatic Movement Disorders -- Psychogenic tremor -- Tremor in childhood -- Part 3: Assessment of tremor: clinical, neurophysiological and neuroimaging aspects -- Assessment of tremor: clinical and functional scales -- Instrumentation: classical and emerging techniques -- Signal processing -- Diffusion imaging in tremor -- The metabolic networks in Parkinson's disease -- Part 4: Therapies of tremor -- Pharmacological treatments of tremor -- Thalamotomy -- Brain Stimulation -- Dopaminergic Influences on Rest and Action Tremors and Emerging Therapies for Tremor.
520			_aTremor is intimately linked to the numerous interactions of the central and peripheral nervous system components tuning motor control, from the cerebral cortex up to the peripheral effectors. Activities of central generators, reflex loop delays, inertia, stiffness and damping are all factors influencing features of tremor. This book discusses the pathophysiology of tremor including membrane mechanisms and rodent models, the advances in genetics and the musculoskeletal models pertinent to body oscillations. The main forms of tremor encountered during clinical practice are considered, taking into account neuroimaging aspects. The book covers recent advances in methodologies and techniques of assessment, and provides practical informations for the daily management. In addition to pharmacological treatments, neurosurgical approaches such as deep brain stimulation (DBS) and thalamotomy are discussed. Emerging techniques under development are also introduced. Future challenges are also presented.
650		0	_aMedicine.
650		0	_aNeurology.
650	1	4	_aBiomedicine.
650	2	4	_aBiomedicine general.
650	2	4	_aNeurology.
700	1		_aGrimaldi, Giuliana. _eeditor.
700	1		_aManto, Mario. _eeditor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9781461440260
830		0	_aContemporary Clinical Neuroscience
856	4	0	_uhttp://dx.doi.org/10.1007/978-1-4614-4027-7
912			_aZDB-2-SBL
942			_2Dewey Decimal Classification _ceBooks
999			_c44010 _d44010