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008 121026s2013 xxu| s |||| 0|eng d
020 _a9781461456872
_9978-1-4614-5687-2
024 7 _a10.1007/978-1-4614-5687-2
_2doi
050 4 _aQH588.S83
072 7 _aPSAK
_2bicssc
072 7 _aSCI017000
_2bisacsh
072 7 _aSCI049000
_2bisacsh
082 0 4 _a571.6
_223
100 1 _aYildirim, Sibel.
_eauthor.
245 1 0 _aDental Pulp Stem Cells
_h[electronic resource] /
_cby Sibel Yildirim.
264 1 _aNew York, NY :
_bSpringer New York :
_bImprint: Springer,
_c2013.
300 _aX, 83 p. 76 illus., 73 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aSpringerBriefs in Stem Cells,
_x2192-8118
505 0 _aDental Evolution -- Tooth development -- Dental Pulp is a Connective Tissue -- Dental Pulp Stem Cells (DPSC) -- Isolation methods of DPSC -- Characterization of DPSC -- Reprogramming of DPSC to induced pluripotent stem cells (iPSC) -- Immunomodulatory effects of DPSC -- Dental Pulp is a Complex Adaptive System.
520 _aStem cell technology is moving forward at a tremendous rate. Recent discoveries have surprised even the most expert researchers. While every piece of new data broadens the current knowledge and contributes to this moving forward, the new data also serve as paradigm shifters of fundamental knowledge of cell biology. While the question ‘What is a Stem Cell’ may now seem to basic to even discuss, there are still some discrepancies, however, between groups in terms of their functional roles. Teeth develop from the ectoderm of the first branchial arch and the ectomesenchyme of the neural crest. Deciduous teeth start to form between the sixth and eighth weeks, and permanent teeth begin to form in the twentieth weeks. Several studies have demonstrated that the pulp from both adult teeth and deciduous teeth contains dental pulp stem cells. Several factors have made them very attractive as a model system for many researchers; they are multipotent, ethically and non-controversially available in large numbers, immuno-compatible, developmentally primitive, easy to isolate and have high expansion potential in vitro. However, many controversies still exist in the field. There are several unanswered questions in the biology of dental pulp and odontoblasts. This new volume in the SpringerBriefs in Stem Cells  series presents an evaluation of stem cells from human dental pulp as a reliable stem cell source for cell-based therapy to stimulate tissue regeneration.
650 0 _aDentistry.
650 0 _aLife sciences.
650 0 _aCell biology.
650 0 _aStem cells.
650 0 _aBiomedical engineering.
650 1 4 _aLife Sciences.
650 2 4 _aStem Cells.
650 2 4 _aCell Biology.
650 2 4 _aDentistry.
650 2 4 _aBiomedical Engineering.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9781461456865
830 0 _aSpringerBriefs in Stem Cells,
_x2192-8118
856 4 0 _uhttp://dx.doi.org/10.1007/978-1-4614-5687-2
912 _aZDB-2-SBL
942 _2Dewey Decimal Classification
_ceBooks
999 _c44435
_d44435