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008 130127s2013 xxu| s |||| 0|eng d
020 _a9781461460152
_9978-1-4614-6015-2
024 7 _a10.1007/978-1-4614-6015-2
_2doi
050 4 _aRB1-214
072 7 _aMMF
_2bicssc
072 7 _aMED067000
_2bisacsh
082 0 4 _a616.07
_223
245 1 0 _aMolecular Pathology of Neoplastic Gastrointestinal Diseases
_h[electronic resource] /
_cedited by Antonia R. Sepulveda, John P. Lynch.
264 1 _aBoston, MA :
_bSpringer US :
_bImprint: Springer,
_c2013.
300 _aX, 277 p.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aMolecular Pathology Library,
_x1935-987X ;
_v7
505 0 _aSection 1. Introduction -- 1. Mechanisms of Gastrointestinal Carcinogenesis -- Section 2. Epithelial Neoplastic Disease -- 2. Targeted Therapies and Molecular Diagnostics of Gastrointestinal Cancers -- 3. Molecular Pathology of Barrett's Metaplasia and Esophageal Adenocarcinoma -- 4. Molecular Pathology of Squamous Carcinomas of the Esophagus -- 5. Molecular Mechanisms and Pathology of Gastric Carcinogenesis: Sporadic Cancers -- 6. Hereditary Diffuse Gastric Cancer and Other Gastric Cancers Associated with Hereditary Predisposition Syndromes -- 7. Cancer Predisposition Syndromes of the Gastrointestinal Tract -- 8. Molecular Pathology of Colon and Small Bowel Cancers: Sporadic Types -- 9. Cancers of the Rectum and Anal Canal -- 10. Molecular Pathology of Inflammatory Bowel Disease Associated Neoplasia -- Section 3. Non-Epithelial Neoplastic  Tumors -- 11. Molecular Biology and Pathology of Gastrointestinal Stromal Tumors -- 12. Neuroendocrine Tumors -- Section 4. Metastatic Disease and Tumor Markers -- 13. Molecular Mechanisms of Tumor Metastases -- 14. Circulating Tumor Cells and Nucleic Acids for Tumor Diagnosis -- 15. Serological Markers of Digestive Tract Cancers.
520 _aMolecular Pathology of Neoplastic Gastrointestinal Diseases  reviews the molecular aspects that characterize the spectrum of neoplastic conditions that affect the gastrointestinal tract, providing the reader with current up-to-date knowledge. For each disease entity chapters provide reviews on: the molecular basis of the individual disease molecular testing approaches currently available or in development for diagnosis or for gene target characterization for selective targeted therapies recommended guidelines for clinical application of molecular tests are included whenever available molecular testing for hereditary predisposition or disease risk animal models and cell culture models of disease   .
650 0 _aMedicine.
650 0 _aGastroenterology.
650 0 _aPathology.
650 1 4 _aMedicine & Public Health.
650 2 4 _aPathology.
650 2 4 _aGastroenterology.
700 1 _aSepulveda, Antonia R.
_eeditor.
700 1 _aLynch, John P.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9781461460145
830 0 _aMolecular Pathology Library,
_x1935-987X ;
_v7
856 4 0 _uhttp://dx.doi.org/10.1007/978-1-4614-6015-2
912 _aZDB-2-SME
942 _2Dewey Decimal Classification
_ceBooks
999 _c44524
_d44524