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020 _a9781461464464
_9978-1-4614-6446-4
024 7 _a10.1007/978-1-4614-6446-4
_2doi
050 4 _aQA276-280
072 7 _aUFM
_2bicssc
072 7 _aCOM077000
_2bisacsh
082 0 4 _a519.5
_223
100 1 _aNagarajan, Radhakrishnan.
_eauthor.
245 1 0 _aBayesian Networks in R
_h[electronic resource] :
_bwith Applications in Systems Biology /
_cby Radhakrishnan Nagarajan, Marco Scutari, Sophie Lèbre.
264 1 _aNew York, NY :
_bSpringer New York :
_bImprint: Springer,
_c2013.
300 _aXIII, 157 p. 36 illus.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aUse R! ;
_v48
505 0 _aIntroduction -- Bayesian Networks in the Absence of Temporal Information -- Bayesian Networds in the Presence of Temporal Information -- Bayesian Network Inference Algorithms -- Parallel Computing for Bayesian Networks -- Solutions -- Index -- References.
520 _aBayesian Networks in R with Applications in Systems Biology introduces the reader to the essential concepts in Bayesian network modeling and inference in conjunction with examples in the open-source statistical environment R. The level of sophistication is gradually increased across the chapters with exercises and solutions for enhanced understanding and hands-on experimentation of key concepts. Applications focus on systems biology with emphasis on modeling pathways and signaling mechanisms from high throughput molecular data. Bayesian networks have proven to be especially useful abstractions in this regards as exemplified by their ability to discover new associations while validating known ones. It is also expected that the prevalence of publicly available high-throughput biological and healthcare data sets may encourage the audience to explore investigating novel paradigms using the approaches presented in the book.
650 0 _aStatistics.
650 0 _aProgramming languages (Electronic computers).
650 1 4 _aStatistics.
650 2 4 _aStatistics and Computing/Statistics Programs.
650 2 4 _aStatistical Theory and Methods.
650 2 4 _aProgramming Languages, Compilers, Interpreters.
700 1 _aScutari, Marco.
_eauthor.
700 1 _aLèbre, Sophie.
_eauthor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9781461464457
830 0 _aUse R! ;
_v48
856 4 0 _uhttp://dx.doi.org/10.1007/978-1-4614-6446-4
912 _aZDB-2-SMA
942 _2Dewey Decimal Classification
_ceBooks
999 _c44634
_d44634