000 03090nam a22004937a 4500
001 sulb-eb0022668
003 BD-SySUS
005 20160413122312.0
007 cr nn 008mamaa
008 130606s2013 xxu| s |||| 0|eng d
020 _a9781461469254
_9978-1-4614-6925-4
024 7 _a10.1007/978-1-4614-6925-4
_2doi
050 4 _aQR46
072 7 _aMMFM
_2bicssc
072 7 _aMED052000
_2bisacsh
082 0 4 _a616.9041
_223
100 1 _aZuber, Peter.
_eauthor.
245 1 0 _aFunction and Control of the Spx-Family of Proteins Within the Bacterial Stress Response
_h[electronic resource] /
_cby Peter Zuber.
264 1 _aNew York, NY :
_bSpringer New York :
_bImprint: Springer,
_c2013.
300 _aV, 49 p. 6 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aSpringerBriefs in Microbiology,
_x2191-5385 ;
_v8
505 0 _aIntroduction -- An overview of Spx -- Regulation of the stress response in Gram-positive bacteria -- Expression of spx is affected by multiple stress stimuli -- Post-transcriptional control of Spx: Redox-dependent activation -- Post-transcriptional control of Spx: Regulated proteolysis -- Targets of Spx-dependent transcriptional activation -- Spx function and bacterial virulence -- Questions and future directions.
520 _aThis SpringerBrief on Spx reviews the investigations that led to the discovery of Spx and its orthologs and ties together the results of various studies that have explored the function and control of spx in Gram-positive organisms.  Spx of Bacillus subtilis has been extensively studied, but very little has been published about it. This book incorporates a number of studies that have been conducted in other Gram positive bacteria, which examined the role of Spx orthologs in stress response, bacterial development and virulence.     The book contains an overview that will introduce the protein and its orthologous forms, its association with RNA polymerase, the species of Gram-positive bacteria in which it is found, and the conditions in which it is abundant and active. Spx is a member of a large group of proteins belonging to the ArsC/Spx protein family, so the review touches upon the bioinformatic support for the protein family composition and its meaning with regard to protein structure/function.   .
650 0 _aMedicine.
650 0 _aMedical microbiology.
650 0 _aVirology.
650 0 _aInfectious diseases.
650 1 4 _aBiomedicine.
650 2 4 _aMedical Microbiology.
650 2 4 _aVirology.
650 2 4 _aInfectious Diseases.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9781461469247
830 0 _aSpringerBriefs in Microbiology,
_x2191-5385 ;
_v8
856 4 0 _uhttp://dx.doi.org/10.1007/978-1-4614-6925-4
912 _aZDB-2-SBL
942 _2Dewey Decimal Classification
_ceBooks
999 _c44760
_d44760