000			03549nam a22004937a 4500
001			sulb-eb0022910
003			BD-SySUS
005			20160413122325.0
007			cr nn 008mamaa
008			130913s2013 xxu| s |||| 0|eng d
020			_a9781461482321 _9978-1-4614-8232-1
024	7		_a10.1007/978-1-4614-8232-1 _2doi
050		4	_aRB155-155.8
050		4	_aQH431
072		7	_aMFN _2bicssc
072		7	_aMED107000 _2bisacsh
082	0	4	_a611.01816 _223
082	0	4	_a599.935 _223
245	1	0	_aMolecular Genetics of Axial Patterning, Growth and Disease in the Drosophila Eye _h[electronic resource] / _cedited by Amit Singh, Madhuri Kango-Singh.
264		1	_aNew York, NY : _bSpringer New York : _bImprint: Springer, _c2013.
300			_aXIV, 368 p. 68 illus., 63 illus. in color. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
505	0		_aEarly eye development: Specification and Determination -- Molecular genetic mechanisms of axial patterning: Mechanistic insights into generation of axes in the developing eye -- Catching the Next Wave: Patterning of the Drosophila Eye by the Morphogenetic Furrow -- Cell Morphogenesis -- Cell Polarity in Drosophila Retina -- Negative regulation for neural patterning in the Drosophila eye -- Cell Adhesion during Drosophila eye development -- Modulation of Developmental Signaling by the Proteostasis Network -- Drosophila eye as a model to study regulation of growth control: The discovery of size control pathways -- Contribution of the Drosophila eye to unraveling the basis of neurodegeneration -- Genetic regulation of early eye development in non-dipteran insects -- Development and evolution of the Drosophila Bolwig’s organ: a compound eye relict -- Index.
520			_aUndoubtedly, Drosophila melanogaster, fruit fly, has proven to be one of the most popular invertebrate model organisms, and the work horse for modern day biologists. Drosophila, a highly versatile model with a genetic legacy of more than a century, provides powerful genetic, cellular, biochemical and molecular biology tools to address many questions extending from basic biology to human diseases.  One of the most important questions in biology focuses on: how does a multi-cellular organism develop from a single-celled embryo? The discovery of the genes responsible for pattern formation has helped refine this question.  Drosophila eye model has been extensively used to study molecular genetic mechanisms involved in patterning and growth. Since the genetic machinery involved in the Drosophila eye is similar to humans, it has been used to model human diseases and homology to eyes in other taxa. This book will discuss molecular genetic mechanisms of pattern formation, axial patterning, growth regulation in Drosophila eye, and more.
650		0	_aMedicine.
650		0	_aHuman genetics.
650		0	_aAnimal models in research.
650	1	4	_aBiomedicine.
650	2	4	_aHuman Genetics.
650	2	4	_aAnimal Models.
650	2	4	_aBiomedicine general.
700	1		_aSingh, Amit. _eeditor.
700	1		_aKango-Singh, Madhuri. _eeditor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9781461482314
856	4	0	_uhttp://dx.doi.org/10.1007/978-1-4614-8232-1
912			_aZDB-2-SBL
942			_2Dewey Decimal Classification _ceBooks
999			_c45002 _d45002