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008 130921s2013 xxu| s |||| 0|eng d
020 _a9781627035989
_9978-1-62703-598-9
024 7 _a10.1007/978-1-62703-598-9
_2doi
050 4 _aQH573-671
072 7 _aPSF
_2bicssc
072 7 _aSCI017000
_2bisacsh
072 7 _aSCI049000
_2bisacsh
082 0 4 _a571.9453
_223
245 1 0 _aStudies on Alzheimer's Disease
_h[electronic resource] /
_cedited by Domenico Praticὸ, Patrizia Mecocci.
264 1 _aTotowa, NJ :
_bHumana Press :
_bImprint: Humana Press,
_c2013.
300 _aXI, 236 p. 34 illus., 29 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aOxidative Stress in Applied Basic Research and Clinical Practice,
_x2197-7224
505 0 _aSection 1: Hypotheses -- Oxidative stress: impact in neuroscience research -- Oxidative stress and Alzheimer’s disease -- Inflammation and Oxidation: a link in Alzheimer’ disease pathogenesis -- GAPDH:β-amyloid mediated iron accumulation in Alzheimer’s disease -- Aβ in mitochondria: one piece in the Alzheimer’s disease puzzle -- The role of the plasma membrane redox system in the pathognesis of Alzheimer’s disease -- Section 2: Mechanisms -- Metal dysfunction in Alzheimer’s disease -- Brain Oxidative Stress in the Pathogenesis and Progression of Alzheimer’s Disease -- Cholesterol metabolism and oxidative stress in Alzheimer’s disease -- Brain hypometabolism, oxidative stress, maternal transmission and risk of late-onset Alzheimer’s disease -- Stress and HPA axis dysfunction in Alzheimer’s disease -- Section 3: Clinics -- Diabetes mellitus and its impact on sporadic Alzheimer’s disease -- Peripheral biomarkers of oxidative tress in Alzheimer’s disease -- Nutrition lifestyle and oxidative stress: prevention in Alzheimer’s disease -- Are antioxidants food and nutrients useful in preventing cognitive decline?.- Antioxidant clinical trials in Mild Cognitive Impairment and Alzheimer’s disease.
520 _aDr. Domenico Praticò received his M.D. from the University of Rome “La Sapienza,” School of Medicine. He is currently a Professor of Pharmacology, Microbiology and Immunology and member of the Center for Translational Medicine at Temple University. His main research interest is oxidative biology with a particular focus on bioactive lipids, their metabolic pathways, and their role as biological mediators of cellular and molecular events in the pathogenesis of human diseases, including neurodegenerative and cardiovascular diseases.   Dr. Patrizia Mecocci received her M.D. from the University of Perugia, School of Medicine. She is currently a Full Professor of Gerontology and Geriatrics and Director of the Geriatric Clinic at the University of Perugia. Her research is devoted mainly to clinical geriatrics, with a specific interest on brain aging and dementia and on age-related biological modifications, with a particular focus on the role of oxidants and antioxidants in neurodegenerative and cardiovascular diseases. .
650 0 _aLife sciences.
650 0 _aGeriatrics.
650 0 _aCell biology.
650 0 _aOxidative stress.
650 1 4 _aLife Sciences.
650 2 4 _aOxidative Stress.
650 2 4 _aCell Biology.
650 2 4 _aGeriatrics/Gerontology.
700 1 _aPraticὸ, Domenico.
_eeditor.
700 1 _aMecocci, Patrizia.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9781627035972
830 0 _aOxidative Stress in Applied Basic Research and Clinical Practice,
_x2197-7224
856 4 0 _uhttp://dx.doi.org/10.1007/978-1-62703-598-9
912 _aZDB-2-SBL
942 _2Dewey Decimal Classification
_ceBooks
999 _c45173
_d45173