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008 130927s2013 xxu| s |||| 0|eng d
020 _a9781627036344
_9978-1-62703-634-4
024 7 _a10.1007/978-1-62703-634-4
_2doi
050 4 _aQH573-671
072 7 _aPSF
_2bicssc
072 7 _aSCI049000
_2bisacsh
082 0 4 _a571.6
_223
245 1 0 _aCell and Molecular Biology of Breast Cancer
_h[electronic resource] /
_cedited by Heide Schatten.
264 1 _aTotowa, NJ :
_bHumana Press :
_bImprint: Humana Press,
_c2013.
300 _aVIII, 383 p. 55 illus., 51 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _a1. Histopathology and grading of breast cancer -- 2. Multicentric/multifocal breast cancer: overview, biology and therapy -- 3. The immune system in breast cancer initiation and progression: role of epithelial to mesenchymal transition -- 4. Remodeling of the extracellular matrix: implications for cancer -- 5. Biology and treatment of basal-like breast cancer -- 6. Re-excision after lumpectomy for breast cancer -- 7. Novel anti-angiogenic therapies using naturally-occurring and synthetic drugs to combat progestin-dependent breast cancer -- 8. New insights on estrogen receptor actions in hormone-responsive breast cancer cells by interaction proteomics -- 9. Reprogramming breast cancer cells with embryonic microenvironments: insights from nodal signaling -- 10. Metastatic determinants: breast tumour cells in circulation -- 11. Breast cancer epigenetics: biomarkers and therapeutic potential -- 12. The impact of centrosome abnormalities on breast cancer development and progression with a focus on targeting centrosomes for breast cancer therapy -- 13. A New Perspective on Cyclin D1: beyond cell cycle regulation -- 14. Gene signatures of inflammatory breast cancer: epithelial plasticity and a cancer stem cell phenotype -- 15. An integrated human mammary epithelial cell culture system for studying carcinogenesis and aging -- 16. New breast cancer treatment considerations – a brief review of the use of genetically modified (attenuated) bacteria as therapy for advanced and metastatic breast cancer.
520 _aHighlighting recent advances in our understanding of breast cancer, this book is intended for a wide audience as a reference book. Included are reviews of genetics, epigenetics, various aspects of cell and molecular biology, and several other areas of breast cancer that are aimed at determining new intervention sites for treatments and cures of the disease. The chapters are written by internationally recognized experts and include reviews of key topics in breast cancer research. Each chapter highlights the new aspects of specific research topics, the various impacts of designing new strategies, and identifies new targets for therapeutic intervention. The topics addressed are selected to be of interest to patients, scientists, students, teachers, and to all who are interested in expanding their knowledge of breast cancer imaging, diagnostics, therapeutics, or basic biomedical research on breast cancer.
650 0 _aLife sciences.
650 0 _aCancer research.
650 0 _aCell biology.
650 0 _aMicroscopy.
650 1 4 _aLife Sciences.
650 2 4 _aCell Biology.
650 2 4 _aBiological Microscopy.
650 2 4 _aCancer Research.
700 1 _aSchatten, Heide.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9781627036337
856 4 0 _uhttp://dx.doi.org/10.1007/978-1-62703-634-4
912 _aZDB-2-SBL
942 _2Dewey Decimal Classification
_ceBooks
999 _c45174
_d45174