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001 | sulb-eb0023161 | ||
003 | BD-SySUS | ||
005 | 20160413122337.0 | ||
007 | cr nn 008mamaa | ||
008 | 130628s2013 sz | s |||| 0|eng d | ||
020 |
_a9783034806794 _9978-3-0348-0679-4 |
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024 | 7 |
_a10.1007/978-3-0348-0679-4 _2doi |
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050 | 4 | _aQH432 | |
072 | 7 |
_aPSVH _2bicssc |
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072 | 7 |
_aPSAK1 _2bicssc |
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072 | 7 |
_aSCI070000 _2bisacsh |
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072 | 7 |
_aSCI029000 _2bisacsh |
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082 | 0 | 4 |
_a591.35 _223 |
100 | 1 |
_aBarrett, Lucy W. _eauthor. |
|
245 | 1 | 0 |
_aUntranslated Gene Regions and Other Non-coding Elements _h[electronic resource] : _bRegulation of Eukaryotic Gene Expression / _cby Lucy W. Barrett, Sue Fletcher, Steve D. Wilton. |
264 | 1 |
_aBasel : _bSpringer Basel : _bImprint: Springer, _c2013. |
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300 |
_aVIII, 56 p. 2 illus. in color. _bonline resource. |
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336 |
_atext _btxt _2rdacontent |
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337 |
_acomputer _bc _2rdamedia |
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338 |
_aonline resource _bcr _2rdacarrier |
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347 |
_atext file _bPDF _2rda |
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490 | 1 |
_aSpringerBriefs in Biochemistry and Molecular Biology, _x2211-9353 |
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505 | 0 | _aIntroduction -- Promoter -- 5’ Untranslated Region -- Structure -- Intronic Regions -- 3’ Untranslated Region -- Non-coding RNAs -- Conclusion. | |
520 | _aThere is now compelling evidence that the complexity of higher organisms correlates with the relative amount of non-coding RNA rather than the number of protein-coding genes. Previously dismissed as “junk DNA”, it is the non-coding regions of the genome that are responsible for regulation, facilitating complex temporal and spatial gene expression through the combinatorial effect of numerous mechanisms and interactions working together to fine-tune gene expression. The major regions involved in regulation of a particular gene are the 5’ and 3’ untranslated regions and introns. In addition, pervasive transcription of complex genomes produces a variety of non-coding transcripts that interact with these regions and contribute to regulation. This book discusses recent insights into the regulatory roles of the untranslated gene regions and non-coding RNAs in the control of complex gene expression, as well as the implications of this in terms of organism complexity and evolution. | ||
650 | 0 | _aLife sciences. | |
650 | 0 | _aMedical genetics. | |
650 | 0 | _aNucleic acids. | |
650 | 0 | _aPlant genetics. | |
650 | 0 | _aAnimal genetics. | |
650 | 1 | 4 | _aLife Sciences. |
650 | 2 | 4 | _aAnimal Genetics and Genomics. |
650 | 2 | 4 | _aPlant Genetics & Genomics. |
650 | 2 | 4 | _aGene Function. |
650 | 2 | 4 | _aNucleic Acid Chemistry. |
700 | 1 |
_aFletcher, Sue. _eauthor. |
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700 | 1 |
_aWilton, Steve D. _eauthor. |
|
710 | 2 | _aSpringerLink (Online service) | |
773 | 0 | _tSpringer eBooks | |
776 | 0 | 8 |
_iPrinted edition: _z9783034806787 |
830 | 0 |
_aSpringerBriefs in Biochemistry and Molecular Biology, _x2211-9353 |
|
856 | 4 | 0 | _uhttp://dx.doi.org/10.1007/978-3-0348-0679-4 |
912 | _aZDB-2-SBL | ||
942 |
_2Dewey Decimal Classification _ceBooks |
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999 |
_c45253 _d45253 |