000 | 03007nam a22005657a 4500 | ||
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001 | sulb-eb0023163 | ||
003 | BD-SySUS | ||
005 | 20160413122337.0 | ||
007 | cr nn 008mamaa | ||
008 | 130828s2013 sz | s |||| 0|eng d | ||
020 |
_a9783034806886 _9978-3-0348-0688-6 |
||
024 | 7 |
_a10.1007/978-3-0348-0688-6 _2doi |
|
050 | 4 | _aQH345 | |
050 | 4 | _aQD415-436 | |
072 | 7 |
_aPSBC _2bicssc |
|
072 | 7 |
_aSCI007000 _2bisacsh |
|
082 | 0 | 4 |
_a572.696 _223 |
100 | 1 |
_aKutikhin, Anton G. _eauthor. |
|
245 | 1 | 0 |
_aGenomics of Pattern Recognition Receptors _h[electronic resource] : _bApplications in Oncology and Cardiovascular Diseases / _cby Anton G. Kutikhin, Arseniy E. Yuzhalin. |
264 | 1 |
_aBasel : _bSpringer Basel : _bImprint: Springer, _c2013. |
|
300 |
_aXI, 185 p. _bonline resource. |
||
336 |
_atext _btxt _2rdacontent |
||
337 |
_acomputer _bc _2rdamedia |
||
338 |
_aonline resource _bcr _2rdacarrier |
||
347 |
_atext file _bPDF _2rda |
||
505 | 0 | _aThe Biology of Toll-like Receptors and NOD-like Receptors: Toggles of Inflammation -- Pattern Recognition Receptors, Gene Polymorphisms, and Cancer: A Double-Edged Sword -- Structural Genomic Variation in Toll-Like Receptor 4 and Cancer -- Structural Genomic Variation in Other Toll-like Receptors and Cancer -- Structural Genomic Variation in Toll-Like Receptor Signaling Pathway and Cancer -- Structural Genomic Variation in Toll-like Receptor Pathway and Prostate Cancer -- Structural Genomic Variation in NOD-Like Receptors and Cancer -- Structural Genomic Variation in Pattern Recognition Receptors and Cardiovascular Diseases -- Hot Spots In the Field: Where Should We Go. | |
520 | _aThis book offers comprehensive information on the polymorphisms of genes encoding pattern recognition receptors (PRRs). Following a short description of the general role of PRRs in the immune system, the structure and function of Toll-like and NOD-like receptors are examined in detail. The main focus is on the role of inherited variation in PRRs and their correlation to cancer and cardiovascular diseases. A review of all epidemiological investigations is included, and a concept of genomic risk markers for the prevention of various diseases is also discussed. | ||
650 | 0 | _aLife sciences. | |
650 | 0 | _aCancer research. | |
650 | 0 | _aHuman genetics. | |
650 | 0 | _aImmunology. | |
650 | 0 | _aCardiology. | |
650 | 0 | _aOncology. | |
650 | 0 | _aProteins. | |
650 | 1 | 4 | _aLife Sciences. |
650 | 2 | 4 | _aReceptors. |
650 | 2 | 4 | _aImmunology. |
650 | 2 | 4 | _aCancer Research. |
650 | 2 | 4 | _aHuman Genetics. |
650 | 2 | 4 | _aOncology. |
650 | 2 | 4 | _aCardiology. |
700 | 1 |
_aYuzhalin, Arseniy E. _eauthor. |
|
710 | 2 | _aSpringerLink (Online service) | |
773 | 0 | _tSpringer eBooks | |
776 | 0 | 8 |
_iPrinted edition: _z9783034806879 |
856 | 4 | 0 | _uhttp://dx.doi.org/10.1007/978-3-0348-0688-6 |
912 | _aZDB-2-SBL | ||
942 |
_2Dewey Decimal Classification _ceBooks |
||
999 |
_c45255 _d45255 |