000 | 02924nam a22005177a 4500 | ||
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001 | sulb-eb0023629 | ||
003 | BD-SySUS | ||
005 | 20160413122400.0 | ||
007 | cr nn 008mamaa | ||
008 | 130517s2013 gw | s |||| 0|eng d | ||
020 |
_a9783642233807 _9978-3-642-23380-7 |
||
024 | 7 |
_a10.1007/978-3-642-23380-7 _2doi |
|
050 | 4 | _aRB155-155.8 | |
050 | 4 | _aQH431 | |
072 | 7 |
_aMFN _2bicssc |
|
072 | 7 |
_aMED107000 _2bisacsh |
|
082 | 0 | 4 |
_a611.01816 _223 |
082 | 0 | 4 |
_a599.935 _223 |
245 | 1 | 0 |
_aEnvironmental Epigenomics in Health and Disease _h[electronic resource] : _bEpigenetics and Disease Origins / _cedited by Randy L Jirtle, Frederick L. Tyson. |
264 | 1 |
_aBerlin, Heidelberg : _bSpringer Berlin Heidelberg : _bImprint: Springer, _c2013. |
|
300 |
_aXV, 302 p. _bonline resource. |
||
336 |
_atext _btxt _2rdacontent |
||
337 |
_acomputer _bc _2rdamedia |
||
338 |
_aonline resource _bcr _2rdacarrier |
||
347 |
_atext file _bPDF _2rda |
||
490 | 1 |
_aEpigenetics and Human Health, _x2191-2262 |
|
520 | _aExposure to environmental toxicants is associated with changes in DNA methylation and gene expression profiles that together can contribute to increased disease susceptibility. The chapters in this volume, Environmental Epigenomics in Health and Disease - Epigenetics and Disease Origins, address a wide range of environmental exposures, such as airborne particulates, cocaine, radiation, tobacco smoke, and xenoestrogens. Particular emphasis is placed on the consequences of environmental exposures during development on epigenetic reprogramming that influences adult disease pathogenesis. Health outcomes associated with these exposures include autoimmune disorders, neurodevelopmental disorders, and cancer. Importantly, dietary supplements and drugs can modify the epigenetic effects induced by these agents, thereby reducing their toxicological impact. The overall purpose of this volume and its companion, Environmental Epigenomics in Health and Disease - Epigenetics and Complex Diseases, is to give readers an overview of how environmental exposures during early development can influence disease formation by disrupting epigenetic processes and developmental programming. | ||
650 | 0 | _aMedicine. | |
650 | 0 | _aCancer research. | |
650 | 0 | _aHuman genetics. | |
650 | 0 | _aMedical genetics. | |
650 | 1 | 4 | _aBiomedicine. |
650 | 2 | 4 | _aHuman Genetics. |
650 | 2 | 4 | _aCancer Research. |
650 | 2 | 4 | _aGene Function. |
700 | 1 |
_aJirtle, Randy L. _eeditor. |
|
700 | 1 |
_aTyson, Frederick L. _eeditor. |
|
710 | 2 | _aSpringerLink (Online service) | |
773 | 0 | _tSpringer eBooks | |
776 | 0 | 8 |
_iPrinted edition: _z9783642233791 |
830 | 0 |
_aEpigenetics and Human Health, _x2191-2262 |
|
856 | 4 | 0 | _uhttp://dx.doi.org/10.1007/978-3-642-23380-7 |
912 | _aZDB-2-SBL | ||
942 |
_2Dewey Decimal Classification _ceBooks |
||
999 |
_c45721 _d45721 |