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020 _a9783642362323
_9978-3-642-36232-3
024 7 _a10.1007/978-3-642-36232-3
_2doi
050 4 _aRC321-580
072 7 _aPSAN
_2bicssc
072 7 _aMED057000
_2bisacsh
082 0 4 _a612.8
_223
245 1 0 _aNeurogenesis and Neural Plasticity
_h[electronic resource] /
_cedited by Catherine Belzung, Peter Wigmore.
264 1 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg :
_bImprint: Springer,
_c2013.
300 _aX, 401 p.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aCurrent Topics in Behavioral Neurosciences,
_x1866-3370 ;
_v15
505 0 _aPreface -- Part 1. Characterization -- Stem Cells. Hippocampal Neurogenesis. Olfactory Neurogenesis. Synaptogenesis. Neurotrophins -- Part 2. Environmental Factors -- Stress. Enrichment. Exercise. Cytotoxic Drugs and Memory -- Part 3. Diseases -- Depression. Addiction. Neurodegeneration -- Part 4. Ageing and Repair -- Ageing. Repair.
520 _aNeurogenesis and synaptogenesis, once thought to occur mainly during development, have now been established as key features of adult brain function.  Together they enable the brain to respond to both internal and external changes, giving the brain a previously unrecognised level of flexibility.  Alterations in these two features can produce improvements in cognition but are also critically involved in the pathological responses of the brain seen in many psychiatric and neurological conditions.  This volume brings together authors working on a wide range of topics to provide an up to date account of the underlying mechanisms and functions of neurogenesis and synaptogenesis in the adult brain.  Ongoing neurogenesis and alterations in synapses are required for many functions of the brain including olfaction and hippocampal dependent memory.  Increased levels of synaptogenesis and neurogenesis are key aspects of the improved cognition seen after environmental enrichment and exercise.  However, changes in these features are also critical to the pathological response of the brain to stress, depression, neurodegeneration and cytotoxic drugs.  With an increasing understanding of the role of neurogenesis and synaptogenesis it is possible to envisage improvements or novel treatments for a number of diseases and the possibility of harnessing these phenomena to reduce the impact of ageing and to provide mechanisms to repair the brain.  .
650 0 _aMedicine.
650 0 _aNeurosciences.
650 0 _aNeurology.
650 0 _aPsychiatry.
650 0 _aPsychopharmacology.
650 0 _aBehavioral sciences.
650 0 _aStem cells.
650 1 4 _aBiomedicine.
650 2 4 _aNeurosciences.
650 2 4 _aStem Cells.
650 2 4 _aBehavioral Sciences.
650 2 4 _aNeurology.
650 2 4 _aPsychopharmacology.
650 2 4 _aPsychiatry.
700 1 _aBelzung, Catherine.
_eeditor.
700 1 _aWigmore, Peter.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783642362316
830 0 _aCurrent Topics in Behavioral Neurosciences,
_x1866-3370 ;
_v15
856 4 0 _uhttp://dx.doi.org/10.1007/978-3-642-36232-3
912 _aZDB-2-SBL
942 _2Dewey Decimal Classification
_ceBooks
999 _c46757
_d46757