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008 130413s2013 au | s |||| 0|eng d
020 _a9783709113684
_9978-3-7091-1368-4
024 7 _a10.1007/978-3-7091-1368-4
_2doi
050 4 _aRM1-950
072 7 _aMMG
_2bicssc
072 7 _aMED071000
_2bisacsh
082 0 4 _a615
_223
245 1 0 _aSphingolipids: Basic Science and Drug Development
_h[electronic resource] /
_cedited by Erich Gulbins, Irina Petrache.
264 1 _aVienna :
_bSpringer Vienna :
_bImprint: Springer,
_c2013.
300 _aVIII, 259 p.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aHandbook of Experimental Pharmacology,
_x0171-2004 ;
_v215
505 0 _aPreface -- Part 1. Basic mechanisms -- Part 2. Drug development.
520 _aSphingolipids are lipid components of the plasma membrane in eukaryotic cells. They have an important function in signaling mechanisms in the cell. This book on sphingolipids provides insights into the basics of sphingolipid biology and drug development, with a particular emphasis on the sphingolipid derivative ceramide. In the first part basic functions of sphingolipids are described, as well as the genetics of important enzymes, sphingolipid metabolism and synthesis. The second part of this first volume focuses on drug development and pharmacology. The book is intended for scientists in pharmacology, biochemistry and cell biology with a focus on biomedical research as well as for clinicians working in pharmacology, oncology, cardiology, neurology and infectious disease. Together with Volume 216 by the same editors, the collection represents a unique, comprehensive work on sphingolipids, providing information on both sphingolipids’ basic biology (including synthesis, metabolism and cell biology) and their important function in a (patho-)physiological context.
650 0 _aMedicine.
650 0 _aCancer research.
650 0 _aMolecular biology.
650 0 _aPharmacology.
650 0 _aOncology.
650 0 _aCell biology.
650 0 _aCell membranes.
650 1 4 _aBiomedicine.
650 2 4 _aPharmacology/Toxicology.
650 2 4 _aMembrane Biology.
650 2 4 _aCancer Research.
650 2 4 _aMolecular Medicine.
650 2 4 _aCell Biology.
650 2 4 _aOncology.
700 1 _aGulbins, Erich.
_eeditor.
700 1 _aPetrache, Irina.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783709113677
830 0 _aHandbook of Experimental Pharmacology,
_x0171-2004 ;
_v215
856 4 0 _uhttp://dx.doi.org/10.1007/978-3-7091-1368-4
912 _aZDB-2-SBL
942 _2Dewey Decimal Classification
_ceBooks
999 _c47929
_d47929