000			03586nam a22004937a 4500
001			sulb-eb0026597
003			BD-SySUS
005			20160413122702.0
007			cr nn 008mamaa
008			130228s2013 ne | s |||| 0|eng d
020			_a9789400758186 _9978-94-007-5818-6
024	7		_a10.1007/978-94-007-5818-6 _2doi
050		4	_aQD431-431.7
072		7	_aPSBC _2bicssc
072		7	_aSCI007000 _2bisacsh
082	0	4	_a572.6 _223
245	1	0	_aProteins of the Nucleolus _h[electronic resource] : _bRegulation, Translocation, & Biomedical Functions / _cedited by Danton H O'Day, Andrew Catalano.
264		1	_aDordrecht : _bSpringer Netherlands : _bImprint: Springer, _c2013.
300			_aVI, 371 p. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
505	0		_aPart I Introduction.- Ch 1 Proteins of the nucleolus -- Part II  The nucleolus and nucleolar proteins -- Ch 2 Functional consequences of nuclear and nucleolar architecture.-  Ch 3 rDNA and nucleologenesis in Drosophila.- Ch 4 The nucleolus of Dictyostelium and other lower eukaryotes -- Ch 5 Human rDNA genes -- Ch 6 Chromatin organization and the mammalian nucleolus -- Ch 7 Chaperones and multitasking proteins in the nucleolus -- Ch 8 Nucleolar localization/retention signals -- Ch 9 Nucleolar transport of putative GTPase GNL1 and related proteins -- Ch 10 Nucleolar protein anchoring and translocation -- Ch 11 The nucleolus as a stress response organelle -- Ch 12 The nucleolar aspect of breast cancer -- Ch 13 Cysteine proteinase inhibitors in the nucleus and nucleolus in activated macrophages -- Ch 14 Nucleolar proteins and cancer -- Ch 15 Nucleolar transplantation and human embryogenesis -- Part V Conclusions -- Ch 16 The nucleolus from its formation to the future.
520			_aThis book contains 14 original review chapters each yielding new, exciting and intriguing data about the emerging understanding of nucleolar structure and function in normal, stressed and diseased cells. The goal of this work is to provide special insight into the nucleolus of the past, present and future, as well its regulation, translocation, and biomedical function. A multitude of topics are introduced and discussed in detail, including nucleologenesis, nucleolar architecture, nucleolar targeting, retention, anchoring, translocation, and the relationship between the nucleolus and cancer. This book also brings together work from several different species, from human to Drosophila to Dictyostelium and other eukaryotic microbes. The final chapter summarizes some of the issues brought up in the various chapters with a view to future research. This book supports the continued emergence of the nucleolus as a dynamic intranuclear region that oversees a vast diversity of events.
650		0	_aLife sciences.
650		0	_aCancer research.
650		0	_aProteins.
650		0	_aMicroscopy.
650	1	4	_aLife Sciences.
650	2	4	_aProtein Science.
650	2	4	_aCancer Research.
650	2	4	_aBiomedicine general.
650	2	4	_aBiological Microscopy.
700	1		_aO'Day, Danton H. _eeditor.
700	1		_aCatalano, Andrew. _eeditor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9789400758179
856	4	0	_uhttp://dx.doi.org/10.1007/978-94-007-5818-6
912			_aZDB-2-SBL
942			_2Dewey Decimal Classification _ceBooks
999			_c48689 _d48689