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020 _a9789400762329
_9978-94-007-6232-9
024 7 _a10.1007/978-94-007-6232-9
_2doi
050 4 _aQD95-96
072 7 _aPNFS
_2bicssc
072 7 _aSCI078000
_2bisacsh
082 0 4 _a543.2-543.8
_223
245 1 0 _aAdvancing Methods for Biomolecular Crystallography
_h[electronic resource] /
_cedited by Randy Read, Alexandre G. Urzhumtsev, Vladimir Y. Lunin.
264 1 _aDordrecht :
_bSpringer Netherlands :
_bImprint: Springer,
_c2013.
300 _aXIII, 362 p. 131 illus.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aNATO Science for Peace and Security Series A: Chemistry and Biology,
_x1874-6489
505 0 _aPart I  Solution Chemistry -- Simple Alkoxide Based Precursor Systems -- Carboxylate Based Precursor Systems -- Mixed Metallo-Organic Precursor Systems -- Single Source Precursor Approach -Hydrolysis Mechanisms in Organic Media -- Aqueous Precursor Systems -- Polymer-Assisted Deposition (PAD) -- Part II Analytical Methods -- Thermal Analysis -- X-ray Absorption Spectroscopy -- Infrared Spectroscopy -- Part III  Deposition Techniques -- Dip Coating -- Spin Coating: Art and Science -- Aerosol Deposition -- Inkjet Printing and Other Direct Writing Methods -- Chemical Bath Deposition -- Part IV Processing and Crystallization.-   Thermodynamics and Heating Processes -- Epitaxial Films -- Orientation and Microstructure Design -- Low-Temperature Processing -- Composite Film Processing -- UV and E-Beam Direct Patterning of Photosensitive CSD Films -- Template Controlled Growth -- Part V Functions and Applications -- Thin Film Multilayer Capacitors -- Base Metal Bottom Electrodes -- Polar Oxide Thin Films for MEMS Applications -- Conducting oxide thin films -- Transparent Conducting Oxides.-  Superconducting Films -- Antireflective Coatings and Optical Filters -- Luminescent Thin Films: Fundamental Aspects and Practical Applications -- Appendix – Syntheses.
520 _aThis work presents a snapshot of the state of the art of modern biomolecular crystallography, from crystallisation through structure determination and even interactive presentation on the web.  Methods driving the latest automated structure determination pipelines are explained, as well as how to deal with problems such as crystal pathologies that still demand expert analysis.  These methods are illustrated through their application to problems of great biological interest, such as the molecular machinery underlying the complement pathway, the mechanism of action of monoamine oxidase inhibitors, and the structure of the eukaryotic ribosome.  Complementary approaches, such as neutron diffraction, small angle X-ray scattering, coherent diffraction and computational modelling, are also explored.
650 0 _aChemistry.
650 0 _aSpectroscopy.
650 0 _aOrganic chemistry.
650 0 _aProteins.
650 0 _aCrystallography.
650 1 4 _aChemistry.
650 2 4 _aSpectroscopy/Spectrometry.
650 2 4 _aProtein Structure.
650 2 4 _aCrystallography.
650 2 4 _aOrganic Chemistry.
700 1 _aRead, Randy.
_eeditor.
700 1 _aUrzhumtsev, Alexandre G.
_eeditor.
700 1 _aLunin, Vladimir Y.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9789400762312
830 0 _aNATO Science for Peace and Security Series A: Chemistry and Biology,
_x1874-6489
856 4 0 _uhttp://dx.doi.org/10.1007/978-94-007-6232-9
912 _aZDB-2-CMS
942 _2Dewey Decimal Classification
_ceBooks
999 _c48809
_d48809