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020 _a9781118347331
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020 _a1118347331
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020 _a9781118347317
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020 _a1118347315
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020 _a9781118347324
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020 _a1118347323
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020 _a9781118347300
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020 _a1118347307
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020 _a1119976685
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035 _a(OCoLC)779097306
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049 _aMAIN
100 1 _aKoskinen, Ari.
245 1 0 _aAsymmetric synthesis of natural products /
_cAri M.P. Koskinen, Department of Chemistry, Aalto University, School of Chemical Technology, Espoo, Finland.
250 _aSecond edition.
260 _aChichester, West Sussex, United Kingdom :
_bWiley,
_c2012.
300 _a1 online resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
520 _a"Natural product synthesis has played a key role in the development of many synthetic methods and will continue to do so in the future. Many recent advances in such diverse fields as immunology, cellular biology and materials science have been achieved through the synthetic chemist's ability to construct often very complicated structures in one enantiomeric form. Asymmetric Synthesis of Natural Products, 2nd Edition introduces students to this rapidly growing field of organic chemistry. The initial chapters present the foundations of asymmetric synthesis, including the theory and applications of individual asymmetric reactions. This is followed by chapters on each of the major individual classes of natural products; their structures, biosynthesis and interrelationships as well as examples of asymmetric syntheses and the practical value of these compounds. Natural product classes covered include carbohydrates, amino acids, peptides, proteins, nucleosides, nucleotides, nucleic acids, polyketides, isoprenoids, shikamic acid derivatives and alkaloids. For this second edition the text has been thoroughly updated and expanded, and includes new discussions and examples covering atom and redox economies, practical aspects and environmental awareness. Organocatalysis has emerged completely in the last ten years, and has been fully integrated into this new edition. Asymmetric Synthesis of Natural Products, 2nd Edition will find a place on the bookshelves of advanced undergraduates and postgraduates working in natural products chemistry, organic synthesis, medicinal chemistry and drug discovery. It is also useful for practising researchers who want to refresh their knowledge of the field"--
_cProvided by publisher.
520 _a"Based on a successful course taught for the last 20 years at universities in the UK, Finland and elsewhere"--
_cProvided by publisher.
504 _aIncludes bibliographical references and index.
588 0 _aPrint version record and CIP data provided by publisher.
505 0 _aAsymmetric Synthesis of Natural Products; Contents; Preface to the First Edition; Preface to the Second Edition; List of Common Abbreviations; Chapter 1 Introduction; 1.1 Some properties of natural products; 1.2 Natural products as drugs; 1.3 Structures of natural products; 1.4 Asymmetric synthesis of natural products; 1.5 Synthetic organic chemistry; References; Chapter 2 Chirality, Topology, and Asymmetric Synthesis; 2.1 The need for enantiopure compounds; 2.2 Determination of enantiomeric purity; 2.3 Chirality and thermodynamic principles of asymmetric induction.
650 0 _aNatural products
_xSynthesis.
650 0 _aAsymmetry (Chemistry)
650 7 _aSCIENCE
_xChemistry
_xOrganic.
_2bisacsh
650 7 _aAsymmetry (Chemistry)
_2fast
_0(OCoLC)fst00819863
650 7 _aNatural products
_xSynthesis.
_2fast
_0(OCoLC)fst01034399
655 4 _aElectronic books.
655 0 _aElectronic books.
655 7 _aElectronic books.
_2local
776 0 8 _iPrint version:
_aKoskinen, Ari.
_tAsymmetric synthesis of natural products.
_bSecond edition.
_dHoboken, New Jersey : Wiley, 2012
_z9781118087206
_w(DLC) 2012008652
856 4 0 _uhttp://onlinelibrary.wiley.com/book/10.1002/9781118347300
_zWiley Online Library [Free Download only for SUST IP]
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