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019 _a794620384
_a823842515
020 _a9783527630905
_q(electronic bk.)
020 _a3527630902
_q(electronic bk.)
020 _a9783527329038
_q(Cloth)
020 _a352732903X
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020 _a9783527630912
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020 _a3527646329
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020 _a9783527646333
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020 _a3527646337
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024 8 _a9786613642585
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035 _a(OCoLC)809920135
_z(OCoLC)794620384
_z(OCoLC)823842515
037 _a10.1002/9783527630905
_bWiley InterScience
_nhttp://www3.interscience.wiley.com
050 4 _aRA1211
060 4 _aQV 600
072 7 _aHEA
_2eflch
082 0 4 _a615.9
_223
049 _aMAIN
245 0 0 _aMetabolism of drugs and other xenobiotics /
_cedited by Pavel Anzenbacher, Ulrich M. Zanger.
260 _aWeinheim :
_bWiley-VCH,
_c2012.
300 _a1 online resource (734 pages)
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
505 0 _aFront Matter -- Biochemistry and Molecular Genetics of Drug Metabolism. Drug-Metabolizing Enzymes₆An Overview / Pavel Anzenbacher, Eva Anzenbacherov̀ -- Cytochromes P450 / F Peter Guengerich -- UDP-Glucuronosyltransferases / Christian P Strassburg, Sandra Kalthoff -- Sulfotransferases / Michael W H Coughtrie -- Glutathione -Transferases / Miroslav Dostalek, Anna-Katarina Stark -- Hydrolytic Enzymes / Bingfang Yan -- Transporting Systems / Anne T Nies, Claudia Resch, Tadashi Namisaki -- Transcriptional Regulation of Human Drug-Metabolizing Cytochrome P450 Enzymes / Zdenek Dvorak -- Importance of Pharmacogenomics / Ulrich M Zanger, Kathrin Klein, Jessica Rieger -- Metabolism of Drugs. Introduction to Drug Metabolism / Ulrich M Zanger -- Central Nervous System Drugs / Pierre Baumann, Christoph Hiemke -- Cardiovascular Drugs / Stephan Riedmaier, Ulrich M Zanger -- Anticancer Drugs / Matthias Schwab, Elke Schaeffeler, Hiltrud Brauch -- Antimicrobial Agents / Chantal Csajka, Oscar Marchetti, Oriol Manuel, Laurent Decosterd, Amalio Telenti -- Drugs against Acute and Chronic Pain / Andrew A Somogyi, Janet K Coller -- Drugs of Abuse (Including Designer Drugs) / Markus R Meyer, Hans H Maurer -- Nicotine Metabolism and its Implications / Andy Z X Zhu, Rachel F Tyndale -- Metabolism of Alcohol and its Consequences / Helmut K Seitz, Sebastian Mueller -- Metabolism of Natural Compounds. Introduction and Overview / Michael Murray -- Flavonoids / Petr Hodek -- St John's Wort (L.) / Miroslav Dostalek, Anna-Katarina Stark -- Food Components and Supplements / Alexandr Parlesak -- Metabolism of Unnatural Xenobiotics. Environmental Pollutants / Marie Stiborova -- Environmental Estrogens / Miroslav Machala, Jan Vondr̀cek -- Biotransformation of Insecticides / Corie A Ellison, Alice L Crane, James R Olson -- Index.
588 0 _aPrint version record.
520 _aA practice-oriented desktop reference for toxicologists and pharmaceutical researchers, this handbook provides systematic coverage of the metabolic pathways of all major classes of xenobiotics in the human body. The first part briefly reviews the main enzyme systems involved in biotransformation and how they are orchestrated in the body, while parts two to four cover the three main classes of xenobiotics: drugs, natural products, environmental pollutants. Selected, well-documented case studies from the most important xenobiotics classes illustrate general principles of metabolism, making this.
504 _aIncludes bibliographical references and index.
650 0 _aXenobiotics
_xMetabolism.
650 0 _aBiotransformation (Metabolism)
650 0 _aToxicology.
650 1 2 _aBiotransformation
_xphysiology.
650 1 2 _aXenobiotics
_xmetabolism.
650 2 2 _aBiological Agents
_xmetabolism.
650 2 2 _aEnvironmental Pollutants
_xmetabolism.
650 2 2 _aPharmaceutical Preparations
_xmetabolism.
650 2 2 _aPharmacokinetics.
650 2 2 _aToxicology.
650 7 _aBiotransformation (Metabolism)
_2fast
_0(OCoLC)fst00832858
650 7 _aToxicology.
_2fast
_0(OCoLC)fst01153364
650 7 _aXenobiotics
_xMetabolism.
_2fast
_0(OCoLC)fst01181975
655 4 _aElectronic books.
700 1 _aAnzenbacher, Pavel.
700 1 _aZanger, Ulrich M.,
_d1955-
710 2 _aWiley InterScience (Online service)
776 0 8 _iPrint version:
_tMetabolism of drugs and other xenobiotics.
_dWeinheim : Wiley-VCH, 2012
_z9783527329038
_w(OCoLC)794620384
856 4 0 _uhttp://onlinelibrary.wiley.com/book/10.1002/9783527630905
_zWiley Online Library [Free Download only for SUST IP]
938 _aCoutts Information Services
_bCOUT
_n22580743
_c125.00 GBP
938 _aYBP Library Services
_bYANK
_n9341157
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