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019 _a828869678
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020 _a9783527651085
_q(electronic bk.)
020 _a352765108X
_q(electronic bk.)
020 _a9783527651115
_q(electronic bk.)
020 _a352765111X
_q(electronic bk.)
020 _a9781299241206
_q(MyiLibrary)
020 _a1299241204
_q(MyiLibrary)
020 _z9783527330737
020 _z3527330739
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035 _a(OCoLC)826637765
_z(OCoLC)828869678
_z(OCoLC)828896125
_z(OCoLC)961601655
_z(OCoLC)962705463
037 _a455370
_bMIL
050 4 _aRM301.25
_b.A53 2013
072 7 _aMED
_x023000
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072 7 _aMED
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082 0 4 _a615.1/9
_223
049 _aMAIN
245 0 0 _aAnalogue-based drug discovery III /
_cedited by János Fischer, C. Robin Ganellin, David P. Rotella.
246 3 _aAnalogue-based drug discovery 3
246 3 _aAnalog-based drug discovery III
264 1 _aWeinheim :
_bWiley-VCH,
_c[2013]
264 4 _c©2013
300 _a1 online resource (xviii, 385 pages) :
_billustrations, portraits
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
588 0 _aOnline resource; title page from PDF title page (viewed June 30, 2014).
505 0 0 _tGeneral Aspects. Pioneer and Analogue Drugs /
_rJanos Fischer, C Robin Ganellin, David P Rotella --
_tCompetition in the Pharmaceutical Drug Development /
_rChristian Tyrchan, Fabrizio Giordanetto --
_tMetabolic Stability and Analogue-Based Drug Discovery /
_rAmit S Kalgutkar, Antonia F Stepan --
_tUse of Macrocycles in Drug Design Exemplified with Ulimorelin, a Potential Ghrelin Agonist for Gastrointestinal Motility Disorders /
_rMark L Peterson, Hamid Hoveyda, Graeme Fraser, Eric Marsault, Rene Gagnon --
_tDrug Classes. The Discovery of Anticancer Drugs Targeting Epigenetic Enzymes /
_rA Ganesan --
_tThienopyridyl and Direct-Acting P2Y Receptor Antagonist Antiplatelet Drugs /
_rJoseph A Jakubowski, Atsuhiro Sugidachi --
_tSelective Estrogen Receptor Modulators /
_rAmarjit Luniwal, Rachael Jetson, Paul Erhardt --
_tDiscovery of Nonpeptide Vasopressin V2 Receptor Antagonists /
_rKazumi Kondo, Hidenori Ogawa --
_tThe Development of Cysteinyl Leukotriene Receptor Antagonists /
_rPeter R Bernstein --
_tCase Studies. The Discovery of Dabigatran Etexilate /
_rNorbert Hauel, Andreas Clemens, Herbert Nar, Henning Priepke, Joanne van Ryn, Wolfgang Wienen --
_tThe Discovery of Citalopram and Its Refinement to Escitalopram /
_rKlaus P Bogeso, Connie Sanchez --
_tTapentadol : From Morphine and Tramadol to the Discovery of Tapentadol /
_rHelmut Buschmann --
_tNovel Taxanes: Cabazitaxel Case Study /
_rHerve Bouchard, Dorothee Semiond, Marie-Laure Risse, Patricia Vrignaud --
_tDiscovery of Boceprevir and Narlaprevir: A Case Study for Role of Structure-Based Drug Design /
_rSrikanth Venkatraman, Andrew Prongay, George F Njoroge --
_tA New-Generation Uric Acid Production Inhibitor: Febuxostat /
_rKen Okamoto, Shiro Kondo, Takeshi Nishino.
504 _aIncludes bibliographical references and index.
520 _a"Most drugs are analogue drugs. There are no general rules how a new drug can be discovered, nevertheless, there are some observations which help to find a new drug, and also an individual story of a drug discovery can initiate and help new discoveries. Volume III is a continuation of the successful book series with new examples of established and recently introduced drugs. The major part of the book is written by key inventors either as a case study or a study of an analogue class. With its wide range across a variety of therapeutic fields and chemical classes, this is of interest to virtually every researcher in drug discovery and pharmaceutical chemistry, and--together with the previous volumes--constitutes the first systematic approach to drug analogue development"--Publisher's website.
650 0 _aDrug development.
650 7 _aMEDICAL
_xDrug Guides.
_2bisacsh
650 7 _aMEDICAL
_xNursing
_xPharmacology.
_2bisacsh
650 7 _aMEDICAL
_xPharmacology.
_2bisacsh
650 7 _aMEDICAL
_xPharmacy.
_2bisacsh
650 7 _aDrug development.
_2fast
_0(OCoLC)fst00898670
655 4 _aElectronic books.
655 7 _aElectronic books.
_2local
700 1 _aFischer, János,
_eeditor.
700 1 _aGanellin, C. R.
_q(C. Robin),
_eeditor.
700 1 _aRotella, David P.,
_eeditor.
776 0 8 _iPrint version:
_tAnalogue-based drug discovery III.
_dWeinheim : Wiley-VCH, [2013]
_z9783527330737
_w(OCoLC)825555931
856 4 0 _uhttp://onlinelibrary.wiley.com/book/10.1002/9783527651085
_zWiley Online Library [Free Download only for SUST IP]
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