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_aHigh-Density Lipoproteins : _bStructure, Metabolism, Function, and Therapeutics / _cedited by Anatol Kontush, M. John Chapman ; illustrations by Alexander Marienko. |
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_aHoboken, N.J. : _bJohn Wiley & Sons, Inc., _c©2012. |
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_a1 online resource (xxxvi, 605 pages) : _billustrations (some color) |
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504 | _aIncludes bibliographical references and index. | ||
505 | 0 | _aNormal functional HDL -- Functionally defective HDL -- Therapeutic normalisation of subnormal levels and defective biological activities of HDL. | |
588 | 0 | _aPrint version record. | |
520 | _aA complete guide to the role of high-density lipoproteins (HDL) in new and emerging therapies With high-density lipoproteins (HDL) playing an increasing role in cardiovascular disease prevention, there is a growing need for an in-depth look at HDL and its clinical value. This book summarizes the current state of knowledge in the field, providing for the first time a comprehensive, systematic, stylistically coherent, and up-to-date review of the composition, structure, heterogeneity, metabolism, epidemiology, genetics, and function of HDL. Divided into three main parts, High-Density Lipoproteins first examines normal HDL particles, then describes defective HDL, and finally addresses the therapeutic normalization of subnormal levels and defective biological activities of this lipoprotein class. The book highlights the functional properties of HDL, which are relevant to the pathophysiology of atherosclerosis and thrombosis, and discusses the compositional and metabolic heterogeneity of HDL particles. Readers will come away with a clear understanding of the role of HDL in biological processes, the potential value of functional HDL as a therapeutic target, and how current and emerging therapies are poised to influence the treatment of heart disease in the future. | ||
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_aHigh density lipoproteins _xMetabolism. |
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_aCardiovascular system _xDiseases _xTreatment. |
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_aLipoproteins, HDL _xmetabolism. |
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_aArteriosclerosis _xphysiopathology. |
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_aCardiovascular Diseases _xtherapy. |
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_aLipoproteïnes de densitat alta _xMetabolisme. |
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_aSistema cardiovascular _xMalalties _xTractament. |
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_aLipoproteïnes _xMetabolisme. |
650 | 0 | 4 | _aAterosclerosi. |
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_aSistema cardiovascular _xMalalties. |
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655 | 4 | _aElectronic books. | |
655 | 4 | _aLlibres electrònics. | |
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700 | 1 | _aKontush, Anatol. | |
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_aChapman, M. John, _d1945- |
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_iPrint version: _tHigh-density lipoproteins. _dHoboken, N.J. : John Wiley & Sons, Inc., ©2012 _z9780470408216 _w(DLC) 2011026194 _w(OCoLC)743275863 |
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