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_aSCI _x013040 _2bisacsh |
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082 | 0 | 4 |
_a547.2 _223 |
049 | _aMAIN | ||
245 | 0 | 0 |
_aCopper-catalyzed asymmetric synthesis / _cedited by Alexandre Alexakis, Norbert Krause, Simon Woodward. |
264 | 1 |
_aWeinheim : _bWiley-VCH, _c2014. |
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300 |
_a1 online resource (xvi, 454 pages) : _billustrations |
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_atext _btxt _2rdacontent |
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_acomputer _bc _2rdamedia |
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338 |
_aonline resource _bcr _2rdacarrier |
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588 | 0 | _aPrint version record. | |
505 | 0 | _a1. The primary organometallic in copper-catalyzed reactions / Simon Woodward -- 2. Copper-catalyzed asymmetric conjugate addition / Alexandre Alexakis, Norbert Krause and Simon Woodward -- 3. Copper-catalyzed asymmetric conjugate addition and allylic substitution of organometallic reagents to extended multiple-bond systems / Matthieu Tis sot, Hailing Li and Alexandre Alexakis -- 4. Asymmetric allylic alkylation / Olivier Baslé, Audrey Denicourt-Nowicki, Christopohe Crévisy and Marc Mauduit -- 5. Ring opening of epoxides and related systems / Mauro Pineschi -- 6. Carbon-boron and carbon-silicon bond formation / Masaya Sawamura and Hajime Ito -- 7. CuH in asymmetric reductions / Bruce H. Lipshutz -- 8. Asymmetric cyclopropanation and aziridination reactions / André B. Charette, Hélène Lebel and Marie-Noelle Roy -- 9. Copper-catalyzed asymmetric addition reaction of imines / Kiyoshi Tomioka, Ken-ichi Yamada and Yasutomo Yamamoto -- 10. Carbometallation reactions / Dorian Didier and Ilan Marek -- 11. Chiral copper Lewis acids in asymmetric transformations / Shinya Adachi, Ramkumar Moorthy and Mukund P. Sibi -- 12. Mechanistic aspects of copper-catalyzed reactions / Per-Fredrik Larsson, Per-Ola Norrby and Simon Woodward -- 13. NMR spectroscopic aspects / Felicitas von Rekowski, Carina Koch and Ruth M. Gschwind -- 14. Application to the synthesis of natural products / Beatriz C. Calvo, Jeffrey Buter and Adriaan J. Minnaard. | |
520 | 3 | _aThis book reflects the increasing interest among the chemical synthetic community in the area of asymmetric copper-catalyzed reactions, and introduces readers to the latest, most significant developments in the field. The contents are organized according to reaction type and cover mechanistic and spectroscopic aspects as well as applications in the synthesis of natural products. A whole chapter is devoted to understanding how primary organometallics interact with copper to provide selective catalysts for allylic substitution and conjugate addition, both of which are treated in separate chapters. Another is devoted to the variety of substrates and experimental protocols, while an entire chapter covers the use on non-carbon nucleophiles. Other chapters deal with less-known reactions, such as carbometallation or the additions to imines and related systems, while the more established reactions cyclopropanation and aziridination as well as the use of copper (II) Lewis acids are warranted their own special chapters. Two further chapters concern the processes involved, as determined by mechanistic studies. Finally, a whole chapter is devoted to the synthetic applications. This book is essential reading for researchers at academic institutions and professionals at pharmaceutical or agrochemical companies. | |
504 | _aIncludes bibliographical references at the end of each chapters and index. | ||
650 | 0 | _aAsymmetric synthesis. | |
650 | 0 | _aCopper catalysts. | |
650 | 0 | _aOrganocopper compounds. | |
650 | 0 |
_aOrganic compounds _xSynthesis. |
|
650 | 7 |
_aSCIENCE _xChemistry _xOrganic. _2bisacsh |
|
650 | 7 |
_aAsymmetric synthesis. _2fast _0(OCoLC)fst00819861 |
|
650 | 7 |
_aCopper catalysts. _2fast _0(OCoLC)fst00878447 |
|
650 | 7 |
_aOrganic compounds _xSynthesis. _2fast _0(OCoLC)fst01047668 |
|
650 | 7 |
_aOrganocopper compounds. _2fast _0(OCoLC)fst01047934 |
|
655 | 4 | _aElectronic books. | |
655 | 0 | _aElectronic books. | |
700 | 1 |
_aAlexakis, Alexandre, _eeditor. |
|
700 | 1 |
_aKrause, Norbert, _eeditor. |
|
700 | 1 |
_aWoodward, Simon _c(Professor of Synthetic Organic Chemistry), _eeditor. |
|
776 | 0 | 8 |
_iPrint version: _tCopper-catalyzed asymmetric synthesis _z9783527332045 _w(OCoLC)862092543 |
856 | 4 | 0 |
_uhttp://onlinelibrary.wiley.com/book/10.1002/9783527664573 _zWiley Online Library [Free Download only for SUST IP] |
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