000			06098cam a2200781 i 4500
001			sulb-eb0033938
003			BD-SySUS
005			20170713221423.0
006			m o d
007			cr |||||||||||
008			150617s2015 nju ob 001 0 eng
010			_a 2015024112
040			_aDLC _beng _erda _cDLC _dOCLCF _dN$T _dIDEBK _dYDXCP _dDG1 _dEBLCP _dCDX _dCOO _dDEBBG _dKSU _dRECBK _dCCO _dBD-SySUS
020			_a9781119016724 (pdf)
020			_a111901672X (pdf)
020			_a9781119017103 (epub)
020			_a1119017106 (epub)
020			_z9781118709238 (cloth)
020			_a9781119017127
020			_a1119017122
020			_a1118709233 (cloth)
020			_a9781118709238 (cloth)
029	1		_aAU@ _b000054950152
029	1		_aCHVBK _b357601203
029	1		_aCHBIS _b010598228
029	1		_aGBVCP _b838919863
029	1		_aDEBBG _bBV043397894
035			_a(OCoLC)911200069
042			_apcc
050	0	0	_aRB147.5
072		7	_aSCI _x007000 _2bisacsh
082	0	0	_a572.8/69 _223
049			_aMAIN
245	0	4	_aThe functions, disease-related dysfunctions, and therapeutic targeting of neuronal mitochondria / _cedited by Valentin K. Gribkoff, Elizabeth A. Jonas, J. Marie Hardwick.
263			_a1511
264		1	_aHoboken, New Jersey : _bJohn Wiley & Sons, _c2015.
300			_a1 online resource.
336			_atext _2rdacontent
337			_acomputer _2rdamedia
338			_aonline resource _2rdacarrier
490	0		_aWiley series on neuropharmacology
504			_aIncludes bibliographical references and index.
505	0		_aMitochondrial permeability transition : look from a different angle / N. Brustovetsky -- The mitochondrial permeability transition pore, the c-subunit of the F1Fo ATP synthase, cellular development and synaptic efficiency / E.A. Jonas, G.A. Porter, Jr., G. Beutner, N. Mnatsakanyan and K.A. Alavian -- Mitochondrial channels in neurodegeneration / P.M. Peixoto, K.W. Kinnally and Evgeny Pavlov -- Mitochondrial Ca2+ transport in the control of neuronal functions : molecular and cellular mechanisms / Y.M. Usachev -- AMP-activated protein kinase (AMPK) as a cellular energy sensor and therapeutic target for neuroprotection / P. Weisova, S. Pfeiffer and J.H.M. Prehn -- HDAC6 : a molecule with multiple functions in neurodegenerative diseases / Y. Yan and R. Jiao -- Neuronal mitochondrial transport / A.L. Knight, Y. Chen, T. Sun and Z.-H. Sheng -- Mitochondria in control of hypothalamic metabolic circuits / C.M. Nasrallah and T.L. Horvath -- Mitochondria anchored at the synapse / G.A. Spirou, D. Jackson and G.A. Perkins -- Neuronal mitochondria are different : relevance to neurodegenerative disease / S.B. Berman and J.M. Hardwick -- PINK1 as a sensor for mitochondrial function : dual roles / E.K. Steer, M.K. Dail and C.T. Chu -- A get-together to tear it apart : the mitochondrion meets the cellular turnover machinery / G.-L. McLelland and E.A. Fon -- Mitochondrial involvement in neurodegenerative dementia / L. Bonanni, V. Frazzini, A. Thomas and M. Onofrj -- Neuronal mitochondria as a target for the discovery and development of new therapeutics / V.K. Gribkoff -- Mitochondria as a therapeutic target for Alzheimer's disease / C.H.-L. Hung, S.S.-Y. Chung, S.M.-Y. Lee and R.C.-C. Chang -- Mitochondria in Parkinson disease / G. Arena and E.M. Valente -- Therapeutic targeting of neuronal mitochondria in brain injury / H.M. Yonutas, E.D. Hall and P.G. Sullivan -- The use of fibroblasts from patients with inherited mitochondrial disorders for pathomechanistic studies and evaluation of therapies / D. Soiferman and A. Saada.
588			_aDescription based on print version record and CIP data provided by publisher.
520			_aThis book presents advances in the field of neuronal mitochondria - functions, relation to therapeutics, and pharmacology. For scientists and researchers in both industry and academia, this book provides detailed discussion, examples, and approaches, to illustrate the potential of mitochondria as therapeutic targets for neuronal diseases.- Helps readers understand the regulation of mitochondrial cellular processes, such as substrate metabolism, energy production, and programmed versus sporadic cell death- Offers insights on the development of strategies for targeted therapeutic approaches and potential personalized treatments- Includes examples of mitochondrial drugs, development, and mitochondria-targeted approaches for more efficient treatment methods and further developments in the field- Covers the model systems and approaches needed for the development of new drugs for the central nervous system to provide potential modern therapeutics for neurodegenerative disorders.
650		0	_aMitochondrial pathology.
650		0	_aMitochondria _xFormation.
650		0	_aNervous system _xDiseases _xTreatment.
650		7	_aMitochondria _xFormation. _2fast _0(OCoLC)fst01024017
650		7	_aMitochondrial pathology. _2fast _0(OCoLC)fst01024022
650		7	_aNervous system _xDiseases _xTreatment. _2fast _0(OCoLC)fst01036124
650		7	_aSCIENCE / Life Sciences / Biochemistry _2bisacsh
655		4	_aElectronic books.
700	1		_aGribkoff, Valentin K., _eeditor.
700	1		_aJonas, Elizabeth A., _eeditor.
700	1		_aHardwick, J. Marie, _eeditor.
776	0	8	_iPrint version: _tFunctions, disease-related dysfunctions, and therapeutic targeting of neuronal mitochondria _dHoboken, New Jersey : John Wiley & Sons, 2015 _z9781118709238 _w(DLC) 2015020365
856	4	0	_uhttp://onlinelibrary.wiley.com/book/10.1002/9781119017127 _zWiley Online Library [Free Download only for SUST IP]
938			_aRecorded Books, LLC _bRECE _nrbeEB00665984
938			_aEBSCOhost _bEBSC _n1072256
938			_aIngram Digital eBook Collection _bIDEB _ncis30531487
938			_aYBP Library Services _bYANK _n12622390
938			_aYBP Library Services _bYANK _n12624554
938			_aYBP Library Services _bYANK _n12673842
938			_aEBL - Ebook Library _bEBLB _nEBL4045097
938			_aCoutts Information Services _bCOUT _n30531487
994			_a92 _bDG1
999			_c65590 _d65590