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008			151113s2016 enk ob 001 0 eng
010			_a 2015044701
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019			_a935254348
020			_a9781118760338 (ePub)
020			_a1118760336 (ePub)
020			_a9781118760352 (Adobe PDF)
020			_a1118760352 (Adobe PDF)
020			_z9781118760376 (hardback)
020			_a9781118760369
020			_a1118760360
029	1		_aGBVCP _b855500115
029	1		_aDEBBG _bBV043738151
035			_a(OCoLC)929332125 _z(OCoLC)935254348
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082	0	0	_a612.8 _223
084			_aSCI089000 _2bisacsh
049			_aMAIN
245	0	0	_aMolecular neuroendocrinology : _bfrom genome to physiology / _c[edited by] David Murphy, Harold Gainer.
264		1	_aChichester, West Sussex ; _aHoboken, NJ : _bWiley Blackwell, _c2016.
300			_a1 online resource.
336			_atext _2rdacontent
337			_acomputer _2rdamedia
338			_aonline resource _2rdacarrier
490	1		_aWiley-INF Masterclass in Neuroendocrinology Series
520			_a"Discusses the mechanisms that enhance peptide and protein diversity beyond what is encoded in the genome through post-translational modification"-- _cProvided by publisher.
504			_aIncludes bibliographical references and index.
588			_aDescription based on print version record and CIP data provided by publisher.
505	0		_aTitle Page; Table of Contents; List of Contributors; Series Preface; About the Companion Website; Introduction; Part A: Genome and Genome Expression; CHAPTER 1: Evolutionary Aspects of Physiological Function and Molecular Diversity of the Oxytocin/Vasopressin Signaling System; 1.1 Evolution of peptidergic signaling; 1.2 The discovery of neuropeptide signaling components in the era of genomics; 1.3 Evolutionary aspects of OXT/AVP diversity; 1.4 Physiology of OXT and AVP signaling: from worm to man; 1.5 Perspectives; Acknowledgments; References; CHAPTER 2: The Neuroendocrine Genome:
505	8		_a2.1 The discovery of neuropeptides2.2 Characteristics of neuropeptides; 2.3 Neuropeptide genes in the genome; 2.4 Perspectives; Acknowledgments; References; Further reading; CHAPTER 3: Transcriptome Dynamics; 3.1 Approaching transcriptome dynamics; 3.2 Transcriptome dynamics in neuroendocrine systems; 3.3 Transcriptome dynamics in the pineal gland: lessons from different approaches; 3.4 SN-NICHD transcriptome profiling web page; 3.5 Perspectives; References; CHAPTER 4: New Players in the Neuroendocrine System:; 4.1 Non-coding RNA contribution to gene regulation
505	8		_a4.2 Central role of the hypothalamus as a neuroendocrine organ4.3 The pituitary gland and its central control of the peripheral endocrine system; 4.4 The pineal gland -- a connector between external environment and internal homeostasis; 4.5 Perspectives; References; CHAPTER 5: Transcription Factors Regulating Neuroendocrine Development, Function, and Oncogenesis; 5.1 The key players in transcriptional regulation; 5.2 Classes of neuroendocrine-associated TFs; 5.3 REST: a zinc finger TF with complex regulation and diverse function; 5.4 Cooperation of TFs in neuroendocrine phenotype and function
505	8		_a5.5 PerspectivesReferences; CHAPTER 6: Epigenetics; 6.1 Introduction; 6.2 Early life adversity shapes the HPA axis; 6.3 Epigenetic mechanisms: changes in the regulation of gene activity and expression that are not dependent on gene sequence; 6.4 Methods of epigenetic analysis; 6.5 Alterations in epigenetic processes; 6.6 The epigenome and early life adversity; 6.7 Perspectives; References; Further reading; Part B: Proteins, Posttranslational Mechanisms, and Receptors; CHAPTER 7: Proteome and Peptidome Dynamics; 7.1 Introduction; 7.2 Classic neuropeptides and proteins in the RSP
505	8		_a7.3 Techniques used to study the rate of peptide biosynthesis7.4 Dynamics of intracellular proteins and peptides; 7.5 Perspectives; References; CHAPTER 8: Neuropeptidomics; 8.1 Neuropeptides -- one gene, multiple products; 8.2 Mining the neuropeptidome 21st-century style using mass spectrometry-based 'omics approaches; 8.3 What do all these peptides do? Follow-up functional studies; 8.4 Perspectives; Acknowledgments; References; Further reading; CHAPTER 9: Posttranslational Processing of Secretory Proteins; 9.1 Posttranslational modifications of secretory proteins
650		0	_aNeuroendocrinology _xMolecular apects.
650		7	_aSCIENCE / Life Sciences / Neuroscience. _2bisacsh
655		4	_aElectronic books.
655		0	_aElectronic books.
700	1		_aMurphy, David, _d1957- _eeditor.
700	1		_aGainer, Harold, _eeditor.
776	0	8	_iPrint version: _tMolecular neuroendocrinology _dChichester, West Sussex ; Hoboken, NJ : John Wiley & Sons, Inc., 2016 _z9781118760376 _w(DLC) 2015031889
830		0	_aWiley-INF Masterclass in Neuroendocrinology Series.
856	4	0	_uhttp://onlinelibrary.wiley.com/book/10.1002/9781118760369 _zWiley Online Library [Free Download only for SUST IP]
938			_aEBSCOhost _bEBSC _n1134280
938			_aYBP Library Services _bYANK _n12773823
938			_aIngram Digital eBook Collection _bIDEB _ncis32657337
938			_aYBP Library Services _bYANK _n11225771
938			_aEBL - Ebook Library _bEBLB _nEBL4305696
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