| 000 | 02624nam a22002897a 4500 | ||
|---|---|---|---|
| 001 | sulb0067742 | ||
| 003 | BD-SySUS | ||
| 005 | 20180924123554.0 | ||
| 008 | 180924t20152015nyua b 001 0 eng d | ||
| 020 | _a9780815342441 (paperback) | ||
| 020 | _a0815342446 (paperback) | ||
| 040 |
_aDLC _beng _cDLC _erda _dDLC _dBD-SySUS |
||
| 082 | 0 | 0 |
_a571.74 _222 _bLIC |
| 100 | 1 |
_aLim, Wendell, _eauthor. _929621 |
|
| 245 | 1 | 0 |
_aCell signaling : _bprinciples and mechanisms / _cWendell Lim, Bruce Mayer, Tony Pawson. |
| 300 |
_axvi, 400 pages : _bcolor illustrations ; _c28 cm + _e1 poster (color illustrations, both sides ; 71 x 53 cm) |
||
| 505 | 0 | _aIntroduction to cell signaling -- Principles and mechanisms of protein interactions -- Signaling enzymes and their allosteric regulation -- Role of post-translational modifications in signaling -- Subcellular localization of signaling molecules -- Second messengers: small signaling mediators -- Membranes, lipids, and enzymes that modify them -- Information transfer across the membrane -- Regulated protein degradation -- Modular architecture and evolution of signaling proteins -- Information processing by signaling devices and networks -- How cells make decisions -- Methods for studying signaling proteins and networks. | |
| 520 | _a"Cell Signaling presents the principles and components that underlie all known signaling mechanisms. The book provides undergraduate and graduate biology students with the tools needed to make sense of the array of specific pathways used by the cell to communicate. As each concept is explained, numerous examples derived from known signaling mechanisms are used to illustrate the key points. It describes basic signaling mechanisms such as protein interactions, changes in enzyme activity, post-translational modifications, subcellular localization of signaling molecules, and small diffusible signaling mediators. The book also explores the components of signaling pathways and how they are "wired" into pathways and circuits that can process information. The book concludes with a unique chapter that presents extended examples in which specific problems encountered in signaling are introduced and solved, followed by a chapter on methods"-- | ||
| 650 | 0 |
_aCell interaction. _929622 |
|
| 650 | 0 |
_aCellular signal transduction. _929623 |
|
| 650 | 7 |
_aSCIENCE / General. _2bisacsh _929624 |
|
| 650 | 7 |
_aSCIENCE / Life Sciences / Biology / General. _2bisacsh _929625 |
|
| 650 | 7 |
_aSCIENCE / Life Sciences / Cytology. _2bisacsh _929626 |
|
| 700 | 1 |
_aMayer, Bruce, _eauthor. _929627 |
|
| 700 | 1 |
_aPawson, T. , _eauthor. _929628 |
|
| 942 |
_2ddc _cBK |
||
| 999 |
_c73409 _d73409 |
||