000			03557pam a22004211i 4500
001			sulb0073239
003			BD-SySUS
005			20200316162914.0
006			m || d |
007			cr |||||||||||
008			151210s2016 si o 000|0|eng|d
015			_aGBB5I6654 _2bnb
020			_a9789814669337 (PDF ebook) : _c£114.00
020			_z9789814669320 (hbk.) : _c£114.00
035			_a(Uk)017678725
037			_aTANDF_429845 _bIngram Content Group
040			_aStDuBDS _beng _erda _epn _cStDuBDS _dUk
042			_aukblsr
082	0	4	_a572.7 _223 _bUND
245	0	0	_aUnderstanding enzymes : _bfunction, design, engineering and analysis / _cedited by Allan Svendsen.
250			_a1st
264		1	_aSingapore : _bPan Stanford Publishing, _c2016.
300			_a1 online resource.
336			_atext _2rdacontent
337			_acomputer _2rdamedia
338			_aonline resource _2rdacarrier
500			_aAcademic
505	0		_aA practical guide to the quantitative analysis of engineered enzymes. Protein Conformational Motions - Enzyme Catalysis. Enzymology meets Nanotechnology: Single-molecule methods for observing enzyme kinetics in real time. Interfacial enzyme function visualized using neutron, x-ray and light scattering methods. Folding dynamics and structural basis of the enzyme mechanism of ubiquitin C-terminal hydroylases. Stabilisation of Enzymes by metal binding: Structures of Alkalophilic Bacillus proteinases and analysis of the second metal binding site of subtilases. Structure and Functional Roles of Surface Binding Sites in Amylolytic Enzymes. Interfacial Enzymes and their Interactions with Surfaces: Molecular Simulation Studies. Sequence, structure, function: What we learn from analyzing protein families. Bioinformatic analysis of protein families to select function-related variable positions. Decoding life secrets in sequences by chemicals. Role of tunnels and gates in enzymatic catalysis. Molecule descriptors for the structureal analysis of enzyme active sites. Hydration effects on enzyme properties in nonaqueous media analysed by MD simulations. Understanding esterase and amidase reaction specificities by molecular modelling. Towards new non-natural TIM-barrel enzymes using computational design and directed evolution approaches. Handling the Numbers Problem in Directed Evolution. Hints from Nature: Metagenomics in Enzyme Engineering. A functional and structural assessment of circularly permuted Bacillus circulans xylanase and Candida antarctica lipase B. Ancestral Reconstruction in Enzymes. High throughput screening or selection methods for evolutionary enzyme engineering. Nanoscale Enzyme Screening Technologies. Computational Enzyme Engineering: Activity Screening using Quantum Chemistry. In silico screening of enzyme variants by molecular dynamics simulation. Kinetic and thermodynamic stability of variant enzymes.
506	1		_aLegal Deposit; _cOnly available on premises controlled by the deposit library and to one user at any one time; _eThe Legal Deposit Libraries (Non-Print Works) Regulations (UK). _5UkOxU
540			_aRestricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force. _5UkOxU
588			_aDescription based on CIP data; item not viewed.
650		0	_aEnzymes. _935238
700	1		_aSvendsen, Allan, _eeditor. _935239
776	0	8	_iPrint version : _z9789814669320
942			_2ddc _cBK
999			_c75154 _d75154