000 05424cam a22007691a 4500
001 022500447
003 BD-SySUS
005 20230618123643.0
006 m o d
007 cr cn|||||||||
008 100225s2010 enk o 000 0 eng d
015 _aGBB6H2278
_2bnb
016 7 _a015362395
_2Uk
016 7 _a017549262
_2Uk
020 _a9780123694287
020 _a0123694280
020 _a9780080919041
020 _a0080919049
035 _a(OCoLC)528581479
_z(OCoLC)647909617
037 _a114093:114186
_bElsevier Science & Technology
_nhttp://www.sciencedirect.com
040 _aOPELS
_beng
_epn
_cOPELS
_dCDX
_dOCLCQ
_dUKMGB
_dOCLCF
_dE7B
_dOCLCQ
_dU3W
_dD6H
_dAU@
_dOCLCO
_dLEAUB
_dWURST
_dOCLCA
_dS2H
_dOCLCO
_dBD-SySUS
049 _aEQOA
050 4 _aRB43.7
_b.M654 2010
060 4 _a2010 B-216
060 4 _aQY 25
_bM71774 2010
072 7 _aSCI
_x013020
_2bisacsh
072 7 _aMED
_x014000
_2bisacsh
082 0 4 _a616.0756
_222
092 _aWMS528581479
245 0 0 _aMolecular diagnostics :
_btechniques and applications for the clinical laboratory /
_cedited by Wayne W. Grody [and others].
260 _aLondon :
_bAcademic,
_c©2010.
300 _a1 online resource.
504 _aIncludes bibliographical references and index.
505 0 _aI. Introduction and Methodology -- Quantivative PCR: an introduction -- Signal Amplification Methods in Molecular Diagnostics -- The Lab-on-a-Chip Approach for Molecular Diagnostics -- Nucleic Extraction and Amplification -- General Procedures -- II. Quality Assurance, Regulatory, and Ethical Issues -- Billing and Reimbursement for Molecular Diagnostics -- Molecular Pathology and Infectious Diseases -- Ethical Considerations in Molecular Diagnostics -- Quality Control, Assurance, Identification and Standards -- III. Genetic Disease -- Molecular Testing for Cystic Fibrosis and CFTR-Related Conditions -- Carrier Testing for Neurogenetic Diseases -- Hemochromatosis -- Standards and Recommendations for Molecular Diagnostic Testing for Huntington Disease, the Autosomal Dominant Spinocerebellar Ataxias, and Friedreich Ataxia -- IV. Cancer -- The Role of Micro-RNAs in Cancer -- Molecular Diagnostics in the Evaluation of Cancer: Modern Concepts and Overview -- Gene Expression Analysis for Tumor Profiling GEA for TP -- Molecular Diagnostics of Hematopoetic Malignancies -- V. Infectious Diseases -- Viruses -- Hepatic B and C Viruses -- Molecular Diagnosis of Cytomegalovirus -- Molecular Detection of Multiple Respiratory Viruses -- Bacteria -- Molecular Methods for Identification and Characterization of Acinetobacter species -- Molecular Detection and Surveillance of Healthcare-Associated Infections -- Molecular Detection Of Group B Streptococcus -- Role of Molecular Techniques in the Epidemiologic Investigation Of Hospital-Acquired Infections -- Human Papilloma Virus and its Role in Cervical Carcinoma -- VI. Specialized Applications of Molecular Testing -- Molecular HLA Typing Methods Used in Clinical Laboratories -- Identification through DNA analysis in criminal and family relatedness investigations -- VII. Pharmacogenetics -- Overview of Pharmacogenomics and Applications for the Modern Clinical Laboratory -- UDP-Glucuronosyltransferase 1A1 and the Glucuronidation in Oncology Applications and Hyperbilirubinemia -- Pharmacogenetics of P-450 Enzymes -- Pharmacogenomics of Thiopurine Methyl Transferase (TPMT): Importance in Monitoring of Mercaptopurine/Azathioprine Therapy.
520 _aAdvances in genomic and proteomic profiling of disease have transformed the field of molecular diagnostics, thus leading the way for a major revolution in clinical practice. While the range of tests for disease detection and staging is rapidly expanding, many physicians lack the knowledge required to determine which tests to order and how to interpret results. This handbook provides a complete guide to the use and interpretation of molecular testing in the clinical arena. No other available resource offers this emphasis, comprehensive scope, and practical utility in the clinical setting.
650 0 _aMolecular diagnosis.
_962235
650 0 _aPathology, Molecular.
_962236
650 0 _aMedical genetics.
_962237
650 1 2 _aMolecular Diagnostic Techniques.
_962238
650 2 2 _aGenetics, Medical.
_962239
650 2 2 _aPathology, Molecular.
_962240
650 7 _aSCIENCE
_xChemistry
_xClinical.
_2bisacsh
_962241
650 7 _aMEDICAL
_xClinical Medicine.
_2bisacsh
_962242
650 7 _aMedical genetics.
_2fast
_962243
650 7 _aMolecular diagnosis.
_2fast
_962244
650 7 _aPathology, Molecular.
_2fast
_962245
653 0 0 _amoleculaire diagnostiek
653 0 0 _amolecular diagnostics
653 0 0 _adiagnostiek
653 0 0 _adiagnostics
653 0 0 _agenomica
653 0 0 _agenomics
653 0 0 _aeiwitexpressieanalyse
653 0 0 _aproteomics
653 0 0 _adiagnose
653 0 0 _adiagnosis
653 0 0 _atesten
653 0 0 _atesting
653 1 0 _aHuman Pathology
653 2 0 _aMolecular Biology (General)
653 1 0 _aHumane pathologie
653 2 0 _aMoleculaire biologie (algemeen)
700 1 _aGrody, Wayne W.
_962246
776 0 8 _iPrint version:
_tMolecular diagnostics.
_dLondon : Academic, ©2010
_z9780123694287
_z0123694280
_w(OCoLC)422753271
856 4 0 _3ScienceDirect All Books
_uhttps://www.sciencedirect.com/science/book/9780123694287
942 _2ddc
_cEBK
999 _c84842
_d84842