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010 _a 2016944588
016 7 _a101701102
_2DNLM
020 _a9780128023020
_qElectronic bk
020 _a0128023023
_qpaperback
040 _aNLM
_beng
_cNLM
_erda
_dYDXCP
_dBDX
_dTKN
_dOCLCF
_dBTCTA
_dOCLCO
_dNLM
_dOCLCO
_dDLC
050 0 0 _aQR189
_b.H862 2017
060 0 0 _a2017 B-458
060 1 0 _aQW 805
082 _a614.473
130 0 _aHuman vaccines (Modjarrad)
_963516
245 1 0 _aHuman vaccines :
_bemerging technologies in design and development /
_cedited by Kayvon Modjarrad, MD, PhD, Associate Director, Emerging Infectious Disease Threats, Military HIV Research Program/Walter Reed Army Institute of Research, Bethesda, MD, USA, Wayne C. Koff, PhD, President and CEO, Human Vaccines Project, New York, NY, USA.
264 1 _aAmsterdam :
_bElsevier/Academic Press,
_c[2017]
300 _axvii, 191 pages :
_billustrations (some color) ;
_c23 cm
336 _atext
_btxt
_2rdacontent
337 _aunmediated
_bn
_2rdamedia
338 _avolume
_bnc
_2rdacarrier
504 _aIncludes bibliographical references and index.
505 0 _aPart I. Designing vaccines from a new starting point : Broadly neutralizing antibodies / L. Morris and T.A. Moody -- part II. Pathogen free vaccines : Replication-competent viral vectors for vaccines delivery / C.L. Parks ; Reverse vaccinology: exploiting genomes for vaccines design / E. Del Tordello, R. Rappuoli and I. Delany ; Virus-like particle and nanoparticle vaccines / M. Kanekiyo and C.B. Buck -- part III. Immune monitoring : Systems vaccinology / M. Rolland and M.A. Eller ; Immunogenetics and vaccination / M. John, S. Gaudieri and S. Mallal -- part IV. Advanced vaccine development : Methodical considerations / P.B. Gilbert and R. Gottardo ; Vaccine development in special populations / K.M. Edwards and C.B. Creech.
520 _a"Human Vaccines: Emerging Technologies in Design and Development discusses the advances in molecular biology, biophysics, and informatics-among other disciplines-that have provided scientists with the tools to create new vaccines against emerging and re-emerging pathogens. For example, the virus-like particle technologies that led to licensing of highly efficacious HPV vaccines have only come into full realization in the last 10 years. Their success has, in turn, accelerated the pace with which nanoparticle vaccines are being developed Given the rapidity with which the field is changing and the absence of any text documenting this change, there is a need for a resource that surveys these new vaccine technologies, assesses their potential, and describes their applications. This book provides that resource and complements traditional vaccinology books, but also serves as an excellent standalone for researchers and students with basic knowledge in immunology."--
_cProvided by publisher.
530 _aAlso issued online.
650 0 _aVaccines
_xBiotechnology.
_963517
650 0 _aVaccines
_xDesign.
_963518
650 0 _aVaccination.
_963519
650 1 2 _aVaccines.
_963520
650 2 2 _aDrug Discovery
_xtrends.
_963521
650 2 2 _aTechnology, Pharmaceutical
_xtrends.
_963522
650 7 _aVaccination.
_2fast
_0(OCoLC)fst01163544
_963523
650 7 _aVaccines
_xBiotechnology.
_2fast
_0(OCoLC)fst01163574
_963524
650 7 _aVaccines
_xDesign.
_2fast
_0(OCoLC)fst01163576
_963525
700 1 _aModjarrad, Kayvon,
_eeditor.
_963526
700 1 _aKoff, Wayne C.,
_eeditor.
_963527
856 4 _uhttp://www.sciencedirect.com/science/book/9780128023020
_3ELSEVIER
942 _2ddc
_cEBK
999 _c84994
_d84994