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| 003 | BD-SySUS | ||
| 005 | 20230830111945.0 | ||
| 006 | m o d | ||
| 007 | cr cnu|||unuuu | ||
| 008 | 190529t20192019enka ob 001 0 eng d | ||
| 020 |
_a9780128148808 _q(electronic bk.) |
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| 020 |
_a0128148802 _q(electronic bk.) |
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| 020 | _z9780128148792 | ||
| 020 | _a0128148799 | ||
| 020 | _a9780128148792 | ||
| 035 |
_a(OCoLC)1102638945 _z(OCoLC)1229737389 _z(OCoLC)1235825207 |
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| 040 |
_aN$T _beng _erda _epn _cN$T _dN$T _dOPELS _dEBLCP _dUKMGB _dOCLCF _dYDXIT _dYDX _dUKAHL _dOCLCQ _dOCLCO _dOCLCA _dOCLCQ _dERF _dLVT _dVT2 |
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| 050 | 4 |
_aQH450 _b.P35 2019 |
|
| 060 | 4 | _aQU 460 | |
| 072 | 7 | _aSCI | |
| 082 | 0 | 4 |
_a572.865 _223 |
| 100 | 1 |
_aPalacios, Daniela, _eauthor. _963865 |
|
| 245 | 1 | 0 |
_aEpigenetics and regeneration / _cDaniela Palacios. |
| 250 | _aFirst edition. | ||
| 264 | 1 |
_aLondon : _bAcademic Press, _c2019. |
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| 264 | 4 | _c©2019 | |
| 300 | _a1 online resource | ||
| 336 |
_atext _btxt _2rdacontent |
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| 337 |
_acomputer _bc _2rdamedia |
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| 338 |
_aonline resource _bcr _2rdacarrier |
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| 490 | 1 |
_aTranslational epigenetics series ; _vv. 11 |
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| 500 | _aIncludes index. | ||
| 504 | _aIncludes bibliographical references and index. | ||
| 505 | 0 | _aFront Cover; Epigenetics and Regeneration; Copyright; Contents; Contributors; Chapter 1: Epigenetics and Regeneration: An Overview; 1.1. Introduction; 1.2. Epigenetic Regulation of Gene Expression and Cell Fate; 1.3. Development, Reprogramming, and Tissue Regeneration: From the Zygote to Emerging Sources of Multipotent Cells for Re ... ; 1.4. The Epigenetics of Tissue Development, Homeostasis, and Regeneration; 1.5. Epigenetics and Environment: How Age, Environmental Cues, and Epigenetic Drugs Influence The Capability of Stem Cell ... | |
| 505 | 8 | _a1.6. Conclusions: Is There a Place for Epigenetics in Regenerative Medicine?Acknowledgments; List of Abbreviations; References; Section I: Epigenetics: Molecular Players and Mechanisms; Chapter 2: Dynamics and Mechanisms of DNA Methylation Reprogramming; 2.1. Introduction; 2.2. DNA Methylation Machinery; 2.3. DNA Demethylation; 2.4. DNA Methylation in Early Development; 2.5. How Necessary is DNA Methylation Reprogramming for Early Development?; 2.6. DNA Methylation Trajectories During Reprogramming of Somatic Cells; 2.7. 6-Methyldeoxyadenosine in Mammalian DNA?; 2.8. Future Perspectives | |
| 505 | 8 | _aAcknowledgmentsReferences; Chapter 3: Histone Modifications; 3.1. Epigenetics and Chromatin Dynamics; 3.2. Histone Modifications; 3.2.1. Histone Lysine Acetylation; 3.2.2. Histone Lysine Methylation; 3.2.3. Histone Lysine Methylation in Transcription; 3.2.3.1. Gene silencing by histone H3 lysine 9 and lysine 27 methylation; 3.2.3.2. Gene activation by H3 lysine 4 and H3 lysine 36 methylation; 3.2.4. Histone Arginine Methylation; 3.2.5. Histone Phosphorylation; 3.2.6. Histone Ubiquitination; 3.2.7. Histone Sumoylation; 3.2.8. Histone Glycosylation; 3.2.9. Histone Poly-ADP Ribosylation | |
| 505 | 8 | _a3.3. The Histone Code3.3.1. Bivalent Domains, Promoters, and Enhancers; 3.3.2. Histone Modifications and Nuclear Organization; 3.4. Histone Modifications in Cell Fate Changes and Cell Differentiation; 3.4.1. Histone Modifications as Regulators of Neuronal Development and Function; 3.4.2. Histone Mutations in Disease: The Example of Histone Gene Mutations in Brain Tumors; 3.4.3. Histone Modifications in Skeletal Muscle Differentiation and Regeneration; 3.5. Conclusions and Perspectives; List of Abbreviations; References | |
| 505 | 8 | _aChapter 4: Noncoding RNAs as Regulators of Gene Expression in Pluripotency and Differentiation4.1. Introduction; 4.1.1. Classification and Mechanisms of Action; 4.2. The Role of miRNAs in Pluripotency; 4.2.1. miRNAs as Regulators of the Cell Cycle and Apoptosis of Embryonic Stem Cells (ESCs); 4.2.2. miRNAs Regulating the Maintenance of Self-Renewal and Pluripotency of ESCs; 4.2.3. miRNAs in Somatic Cell Reprogramming Towards iPSCs; 4.3. miRNAs as Regulators of Cell Fate and Cell Differentiation; 4.3.1. miRNAs and Regulation of Muscle Differentiation | |
| 588 | 0 | _aOnline resource; title from PDF title page (EBSCO, viewed June 3, 2019). | |
| 650 | 0 |
_aEpigenetics. _963866 |
|
| 650 | 0 |
_aRegeneration (Biology) _963867 |
|
| 650 | 2 |
_aEpigenomics. _963868 |
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| 650 | 7 |
_aSCIENCE _xLife Sciences _xBiochemistry. _2bisacsh _963869 |
|
| 650 | 7 |
_aEpigenetics. _2fast _0(OCoLC)fst01893642 _963870 |
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| 650 | 7 |
_aRegeneration (Biology) _2fast _0(OCoLC)fst01093042 _963871 |
|
| 830 | 0 |
_aTranslational epigenetics series ; _vv. 11. _963872 |
|
| 856 | 4 | 0 |
_3ELSEVIER _uhttps://www.sciencedirect.com/science/book/9780128148792 |
| 942 |
_2ddc _cEBK |
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| 999 |
_c85052 _d85052 |
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