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RNA interference : application to drug discovery and challenges to pharmaceutical development / edited by Paul H. Johnson.

Contributor(s): Material type: TextTextPublication details: Hoboken : John Wiley & Sons, ©2011.Description: xvi, 450 pages : illustrationsContent type:
  • text
Media type:
  • computer
Carrier type:
  • online resource
ISBN:
  • 9780470923733
  • 0470923733
Subject(s): Genre/Form: Additional physical formats: No title; No titleDDC classification:
  • 615/.19 22
LOC classification:
  • RM301.25 .R63 2011
Online resources:
Contents:
Frontmatter -- Color Plates -- Biology of RNA Interference. RNA Interference: What is it? / James A Birchler -- Nucleic Acids as Regulatory Molecules / Faqing Huang, C J Yu, Yanlin Guo -- Use of SiRNA Oligonucleotides to Study Gene Function / Kristin A Wiederholt, Adam N Harris -- Genome Scanning by RNA Interference / Roderick L Beijersbergen, Oliver C Steinbach -- Development of SiRNA for Therapeutic Applications. Discovery of New SiRNA Delivery Agents / Paul H Johnson, Diane Frank, Kunyuan Cui, Roger Adami, Harry Wang, Michael Houston, Steven C Quay -- SiRNA Delivery Vehicles / Aliasger K Salem, Mark A Behlke -- Interferon, Cytokine Induction, and other Potential Toxicities / Adam Judge, Marjorie Robbins, Ian Maclachlan -- Application of RNA Interference to Viral Diseases / Ralph A Tripp, Stephen Mark Tompkins -- Index.
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Frontmatter -- Color Plates -- Biology of RNA Interference. RNA Interference: What is it? / James A Birchler -- Nucleic Acids as Regulatory Molecules / Faqing Huang, C J Yu, Yanlin Guo -- Use of SiRNA Oligonucleotides to Study Gene Function / Kristin A Wiederholt, Adam N Harris -- Genome Scanning by RNA Interference / Roderick L Beijersbergen, Oliver C Steinbach -- Development of SiRNA for Therapeutic Applications. Discovery of New SiRNA Delivery Agents / Paul H Johnson, Diane Frank, Kunyuan Cui, Roger Adami, Harry Wang, Michael Houston, Steven C Quay -- SiRNA Delivery Vehicles / Aliasger K Salem, Mark A Behlke -- Interferon, Cytokine Induction, and other Potential Toxicities / Adam Judge, Marjorie Robbins, Ian Maclachlan -- Application of RNA Interference to Viral Diseases / Ralph A Tripp, Stephen Mark Tompkins -- Index.

Includes bibliographical references and index.

Electronic reproduction. Hoboken, N.J. : Wiley InterScience, 2011. Mode of access: World Wide Web. System requirements: Web browser. Title from title screen (viewed on Jan. 4, 2011). Access may be restricted to users at subscribing institutions.

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